Spots Global Cancer Trial Database for Prospective Observational Study of Antitumor Activity Correlation Between Hormonal Therapy and Expression miRNA100
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Trial Identification
Brief Title: Prospective Observational Study of Antitumor Activity Correlation Between Hormonal Therapy and Expression miRNA100
Official Title: Prospective Observational Study to Evaluate the Correlation Between Antitumor Activity of Hormone Therapy and the Expression of Micro-RNA (miRNA) 100
Study ID: NCT02950207
Conditions
Interventions
Study Description
Brief Summary: Mono-centric, observational, prospective study, designed for pts with diagnosis of hormone-positive breast cancer to evaluate the correlation between the response to hormonal treatment indicated by the reduction of the level of Ki67 and miRNA100 in two groups of patients
Detailed Description: The potential role of miRNAs will be studied as a predictor of hormone sensitivity in hormone-positive breast carcinomas. The miRNA100 obtained on biopsy will be compared with the expression levels of those obtained from the surgically removed tumor, in order to assess the possible modulation of miRNA100 following hormonal treatment.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Fondazione del Piemonte per l'Oncologia-IRCCS Candiolo, Candiolo, Turin, Italy
Contact Details
Name: Filippo Montemurro, MD
Affiliation: FPO-IRCCS
Role: PRINCIPAL_INVESTIGATOR
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