Spots Global Cancer Trial Database for Multiple Oncological Serial Scans Study

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Trial Identification

Brief Title: Multiple Oncological Serial Scans Study

Official Title: The Tumour Bed as Target for Breast Irradiation Following Breast Conserving Surgery

Study ID: NCT01246726

Conditions

Breast Cancer

Interventions

CT SCAN

MRI scan

3D Ultrasound scan

Study Description

Brief Summary: This is a pilot study comparing the appearance and volume of the post surgical region in the intact breast, as determined by 3 modalities: computed Xray tomography (CT), 3 Dimensional ultrasound (USS), Magnetic resonance imaging (MRI) after breast conserving surgery and during whole breast irradiation.

Detailed Description: Consenting patients who have undergone breast conserving surgery and who are planned to receive radiotherapy will have their first MRI and CT scan within 2 weeks of treatment planning. This will be followed by 3 weeks radiotherapy treatment. 3D ultrasound scans will be performed in the first 2 weeks before radiotherapy, during the 2nd and 3rd weeks of radiotherapy and in the 2 weeks following radiotherapy.Following the radiotherapy patients will undergo both CT and MRI scans within 2 weeks of treatment completion.The whole process should take approximately 10 weeks.In this study the CT scans, MRI scan + USS are above standard care and are the additional interventions in this study group.