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Brief Title: CardioPROTECTion With Dapagliflozin in Breast Cancer Patients Treated With AnthrAcycline - PROTECTAA TRIAL
Official Title: A Multicentre, Randomised, Double-blind, Placebo-controlled Phase III Study, Evaluating the Effect of Dapagliflozin on Prevention of Cardiotoxicity in Breast Cancer Patients Undergoing Anthracycline-based Chemotherapy
Study ID: NCT06304857
Brief Summary: The purpose of this study is to evaluate the effect of dapagliflozin on the incidence of cancer therapeutics-related cardiac dysfunction in patients with breast cancer receiving anthracycline treatment.
Detailed Description: This is a multicentre, randomised, double-blind, placebo-controlled phase III study, evaluating the effect of dapagliflozin versus placebo on prevention of cardiotoxicity in breast cancer patients undergoing anthracycline-based chemotherapy.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
4th Military Clinical Hospital with Polyclinic, Wrocław, Dolnośląskie, Poland
Lower Silesian Centre for Oncology, Lung Diseases and Hematology, Wrocław, Dolnośląskie, Poland
Military Medical Institute, Warsaw, Mazowieckie, Poland
Name: Waldemar Banasiak, PhD, MD
Affiliation: 4th Military Clinical Hospital with Polyclinic
Role: PRINCIPAL_INVESTIGATOR