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Spots Global Cancer Trial Database for Using the Active Breathing Control Device to Reduce Radiation Side Effects to Critical Structures in Breast Cancer

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Trial Identification

Brief Title: Using the Active Breathing Control Device to Reduce Radiation Side Effects to Critical Structures in Breast Cancer

Official Title: A Pilot Study Investigating Active Breathing Coordinator (ABC) to Reduce Radiation Dose to Normal Structures in Breast Cancer Patients

Study ID: NCT00328783

Conditions

Breast Cancer

Study Description

Brief Summary: The purpose of this study is to evaluate the use of a device that helps coordinate the breathing cycle in the radiation treatment of the breast in order to minimize the radiation dose to the normal structures around the breast.

Detailed Description: The Active Breathing Coordinator (ABC) allows for temporary and reproducible immobilization of internal thoracic structures by monitoring the patient's breathing cycle and implementing a breath hold at a predefined lung volume level. While ABC is FDA approved and commercially available, only preliminary dosimetric data is available on a small number of patients with breast cancer. There is some data using ABC for intrathoracic malignancies, which shows that it is feasible and safe to use. ABC can be used to optimize the distance between chest wall, heart and liver. This allows adequate treatment of the breast and underlying chest wall while minimizing irradiated cardiac and liver volume.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States

Contact Details

Name: Pramila Rani Anne, MD

Affiliation: Thomas Jefferson University

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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