Spots Global Cancer Trial Database for Pharmacogenomic Study of Neoadjuvant Eribulin for HER2 Non-overexpressing Breast Cancer
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Trial Identification
Brief Title: Pharmacogenomic Study of Neoadjuvant Eribulin for HER2 Non-overexpressing Breast Cancer
Official Title: A Phase II, Open-label, Single-arm, Exploratory Pharmacogenomic Study of Single Agent Eribulin (HALAVEN®) as Neoadjuvant Treatment for Operable Stage I-II HER2 Non-overexpressing Breast Cancer.
Study ID: NCT01669252
Conditions
Interventions
Study Description
Brief Summary: This is a prospective, non-randomized, open-label, multicenter, single-arm exploratory pharmacogenomic study of single agent eribulin as neoadjuvant therapy in patients with operable Stage III HER2 non-overexpressing breast cancer.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Institut Gustave Roussy, Villejuif, , France
Klinikum des Landkreises Deggendorf Frauenklinik Mammazentrum, Deggendorf, , Germany
Brustzentrum im Krankenhaus Köln-Holweide Priv. Doz., Köln, , Germany
Brustzentrum der Universität München, Munic, , Germany
Klinikum Südstadt Rostock, Universitätsfrauenklinik und Poliklinik, Rostock, , Germany
Instituto Portugues de Oncologia de Coimbra Francisco Gentil, EPE, Coimbra, , Portugal
Hospital da Luz, Lisboa, , Portugal
Instituto Portugues de Oncologia de Porto Francisco Gentil, EPE, Porto, , Portugal
Hospital de la Santa Creu i Sant Pau, Barcelona, , Spain
Hospital Universitario Vall d´Hebron, Barcelona, , Spain
Hospital Universitario Vall d´Hebron, Barcelona, , Spain
Complejo Hospitalario de Castellón, Castelló de la Plana, , Spain
Complejo Hospitalario San Pedro de Alcántara, Cáceres, , Spain
Hospital Universitario Reina Sofia, Córdoba, , Spain
Hospital Marina Salud de Denia, Denia, , Spain
Complejo Hospitalario de Jaén, Jaén, , Spain
Hospital Universitari Arnau de Vilanova de Lleida, Lleida, , Spain
Hospital Universitario Ramon y Cajal, Madrid, , Spain
Hospital Universitario Clínico San Carlos, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Hospital Universitario Puerta de Hierro de Majadahonda, Madrid, , Spain
Hospital Universitario Virgen de la Arrixaca, Murcia, , Spain
Hospital Universitari Sant Joan de Reus, Reus, , Spain
Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, , Spain
Hospital Virgen de la Macarena, Sevilla, , Spain
Hospital Universitario Virgen del Rocío, Sevilla, , Spain
Hospital de Torrevieja, Torrevieja, , Spain
Hospital Clinico Universitario de Valencia, Valencia, , Spain
Hospital Arnau de Vilanova de Valencia, Valencia, , Spain
Hospital Universitario Lozano Blesa, Zaragoza, , Spain
Contact Details
Name: Javier Cortés, MD
Affiliation: Hospital Universitario Vall d´Hebron
Role: PRINCIPAL_INVESTIGATOR
Name: Aleix Prat, MD
Affiliation: Vall d´Hebron Institut d´Oncologia
Role: PRINCIPAL_INVESTIGATOR
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