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Spots Global Cancer Trial Database for Breath Test to Predict Breast Cancer and Outcome of Mammography

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Trial Identification

Brief Title: Breath Test to Predict Breast Cancer and Outcome of Mammography

Official Title: Breath Test to Predict Breast Cancer and Outcome of Mammography

Study ID: NCT04755829

Study Description

Brief Summary: To validate a breath test that predicts risk of breast cancer and an abnormal mammogram.

Detailed Description: We will determine the accuracy of volatile organic compounds (VOCs) in the breath as predictors of risk of breast cancer and an abnormal mammogram. Breath samples will be collected using an ultra-clean collection bag and analyzed with gas chromatography surface acoustic wave detection (GC SAW) The study will be performed in two phases: Phase 1: Model-building phase (cross-sectional study): Breath VOCs will be employed to construct multivariate algorithms that distinguish between normal women and those with breast cancer and abnormal screening mammograms. Phase 2: Model-testing phase (cross-sectional study): The predictive accuracy of these algorithms will be tested to predict outcomes in normal women and those with breast cancer and abnormal screening mammograms.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

University of Erlangen, Erlangen, , Germany

Zuyderland Medical Center, Heerlen, , Netherlands

Frimley Health NHS Foundation Trust, Middlesex, , United Kingdom

Contact Details

Name: Alexandra Tenovici

Affiliation: Frimley Health NHS Foundation Trust

Role: PRINCIPAL_INVESTIGATOR

Name: Marc Lobbes, MD

Affiliation: Zuyderland Medical Center

Role: PRINCIPAL_INVESTIGATOR

Name: Peter Fasching, MD

Affiliation: University of Erlangen-Nürnberg

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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