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Brief Title: Study of Cardiac MRI in Patients With Left-Sided Breast Cancer Receiving Radiation Therapy
Official Title: Prospective Pilot Study of Early Markers of Radiation-Induced Cardiac Injury in Patients With Left-Sided Breast Cancer Receiving Photon or Proton Therapy
Study ID: NCT02199366
Brief Summary: This is a pilot study to determine if there are changes in heart function following completion of radiation therapy for breast cancer as measured by cardiac magnetic resonance imaging (cardiac MRI) scans. Additional purposes of this study are to assess cardiac side effects from radiation treatment, evaluate cardiac MRI changes by radiation technique, and compare quality of life questionnaires.
Detailed Description: As part of this study, participants will have a cardiac MRI at baseline and a follow-up cardiac MRI within 1 year after completion of standard radiation therapy for left-sided breast cancer. The cardiac MRI scans will be evaluated to determine if there are changes in cardiac function within 1 year after radiation treatment. Patients will be asked to complete a questionnaire before and after treatment that asks about their health and any symptoms they may be having. Physical exams and any other standard of care service or treatment will be at the discretion of the treating physician.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Florida Proton Therapy Institute, Jacksonville, Florida, United States
Name: Julie A Bradley, MD
Affiliation: University of Florida Proton Therapy Institute
Role: PRINCIPAL_INVESTIGATOR