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Spots Global Cancer Trial Database for Measuring Musculoskeletal Symptoms in Patients Receiving Aromatase Inhibitors

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Trial Identification

Brief Title: Measuring Musculoskeletal Symptoms in Patients Receiving Aromatase Inhibitors

Official Title: Measuring Musculoskeletal Symptoms in Patients Receiving Aromatase Inhibitors

Study ID: NCT01074320

Conditions

Breast Cancer

Interventions

Other

Study Description

Brief Summary: Current guidelines recommend endocrine treatment with aromatase inhibitors (AIs) in post-menopausal women with hormone receptor-positive breast cancer. Musculoskeletal symptoms are commonly reported with AI treatment,however, we do not have consistent methods to measure these symptoms prospectively. This gap in our knowledge inhibits the ability to test and develop treatments for AI-associated musculoskeletal symptoms. This pilot study will evaluate functional tests and standardized instruments for their ability to prospectively assess musculoskeletal symptoms in women being treated with AIs for breast cancer.

Detailed Description: Specific Aims: 1) identify a core set of instruments for measuring musculoskeletal symptoms, 2) model the time course and predictors of change in musculoskeletal symptoms, 3) explore the effect of musculoskeletal symptoms on adherence to AIs in women during the first 6 months of AI treatment. Methods: We will prospectively assess musculoskeletal symptoms due to treatment with aromatase inhibitors. Post-menopausal women beginning AI treatment for hormone responsive breast cancer will be invited to join this study.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: Yes

Locations

North Memorial Medical Center, Robbinsdale, Minnesota, United States

Park Nicollet Institute, St. Louis Park, Minnesota, United States

Contact Details

Name: Karen K Swenson, RN, PhD

Affiliation: HealthPartners Institute

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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