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Spots Global Cancer Trial Database for Docetaxel and Cisplatin Chemotherapy With or Without High Dose Proton Pump Inhibitor in Metastatic Breast Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Docetaxel and Cisplatin Chemotherapy With or Without High Dose Proton Pump Inhibitor in Metastatic Breast Cancer

Official Title: Phase II Study of Docetaxel and Cisplatin Chemotherapy Versus Docetaxel and Cisplatin Chemotherapy Combined With High Dose Proton Pump Inhibitor in Metastatic Breast Cancer

Study ID: NCT01069081

Interventions

Arm C
Arm B
Arm A

Study Description

Brief Summary: The objectives of this study are to evaluate the efficacy and tolerability of high dose proton pump inhibitor combined with chemotherapy in metastatic breast cancer.

Detailed Description: High dose proton pump inhibitor (PPI) has been proved beneficial and it improved efficacy when combined with chemotherapy in preclinical and clinical trials.This study was designed to explore whether adding a proton pump inhibitor into docetaxel and cisplatin chemotherapy improves efficacy and does not affect tolerability in metastatic breast cancer.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Fudan University Cancer Hospital, Shanghai, Shanghai, China

Contact Details

Name: XiChun Hu, MD,Ph. D

Affiliation: Fudan University

Role: PRINCIPAL_INVESTIGATOR

Name: Antonio Chiesi

Affiliation: Istituto Superiore di Sanità

Role: PRINCIPAL_INVESTIGATOR

Name: Stefano Fais, MD PHD

Affiliation: Istituto Superiore di Sanità

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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