Spots Global Cancer Trial Database for Distribution of the Homologous Recombination-related (HRR) Genesmutationsand HRD in Breast Cancer
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Trial Identification
Brief Title: Distribution of the Homologous Recombination-related (HRR) Genesmutationsand HRD in Breast Cancer
Official Title: Landscape Ofhomologous Recombination-related (HRR) Genes Mutations and HRD, and Correlation With Survival in HER2-lowbreast Cance
Study ID: NCT05466786
Interventions
Study Description
Brief Summary: This was a cross-sectional and an observational study, investigator-initiated study in HER2-low breast cancer patients. Approximately 335 subjects will be enrolled in this study to examine the distribution and features of HRD (Homologous recombination deficiency)/HRR (Homologous recombination repair). In this study, investigators plan to clarify the frequency of HRR/HRD in Chinese patients with her2-low breast cancer. In addition, it is planned to investigate any association between invasive disease-free survival (IDFS) / overall survival (OS) and HRD/HRR in her2-low Breast cancer patients.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China
Contact Details
Name: Gong Chang, doctor
Affiliation: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Role: PRINCIPAL_INVESTIGATOR
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