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Brief Title: A Study of MRG002 in Treatment of Advanced HER-2 Positive Breast Cancer Patients
Official Title: An Open-label, Multi-center, Single-arm Phase II Clinical Study to Evaluate the Efficacy and Safety of MRG002 in Advanced HER-2 Positive Breast Cancer Patients Previously Treated With Trastuzumab and TKIs (Magic-009)
Study ID: NCT05263869
Brief Summary: The objective of this study is to assess the safety, efficacy, pharmacokinetics, and immunogenicity of MRG002 in patients with HER2 positive breast cancer with liver metastases.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Fifth Medical Center of PLA General Hospital, Beijing, Beijing, China
Sun Yat-sen Memorial Hospital, Guangzhou, Guangdong, China
Name: Zefei Jiang, MD
Affiliation: Fifth Medical Center of PLA General Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Qiang Liu, MD
Affiliation: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Role: PRINCIPAL_INVESTIGATOR