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Brief Title: Acute Exercise Intervention in Breast Cancer Survivors
Official Title: Acute Effects of Exercise on Breast Cancer Biomarkers (ACE) Study
Study ID: NCT03779867
Brief Summary: This trial studies how a 45-minute bout of acute exercise in women with a history of breast cancer can affect factors associated with breast cancer and help doctors learn more about how exercise can help prevent breast cancer. In an earlier part of the study, investigators looked at the effects of the same intervention in women without a history of cancer.
Detailed Description: OUTLINE: Participants are randomized to 1 of 2 arms. ARM I: Participants undergo a moderate-intensity acute exercise bout over 45 minutes. ARM II: Participants rest by sitting for 45 minutes. EXTENSION: After completion of initial study recruitment and data collection, an extension was approved in 2023. EXTENSION OUTLINE: Participants are randomized to 1 of 2 arms. EXTENSION ARM I: Participants exercise on a stationary bike for 45 minutes. EXTENSION ARM II: Participants rest by sitting for 45 minutes.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: Yes
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States
Name: Anne McTiernan
Affiliation: Fred Hutch/University of Washington Cancer Consortium
Role: PRINCIPAL_INVESTIGATOR