Spots Global Cancer Trial Database for CAREFOR: Precision Medicine Driving Precision Nutrition for the Treatment of NeoAdjuvant Breast Cancer
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Trial Identification
Brief Title: CAREFOR: Precision Medicine Driving Precision Nutrition for the Treatment of NeoAdjuvant Breast Cancer
Official Title: CAREFOR Study: Precision Nutrition Caloric Restriction for Oncology Research: Precision Medicine Driving Precision Nutrition During Neoadjuvant Chemotherapy for Breast Cancer
Study ID: NCT02827370
Conditions
Interventions
Study Description
Brief Summary: The purpose of the study is to determine if a targeted dietary change can enhance the effect of neo-adjuvant chemotherapy
Detailed Description: Primary objective: I To determine if dietary alternations designed to downregulate the dominate molecular drivers of an individuals' breast cancer will enhance the effect of neoadjuvant chemotherapy and allow for an increase in the pathologic complete response rate. Secondary objectives I) Investigator measurable changes to molecular and patient characteristics from precision nutrition to determine a metric for evaluation this treatment in future studies.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Sidney Kimmel Cancer Center at Thomas Jefferson Univeristy, Philadelphia, Pennsylvania, United States
Contact Details
Name: Nicole Simone, MD
Affiliation: Thomas Jefferson University
Role: PRINCIPAL_INVESTIGATOR
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