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Brief Title: Tesetaxel as First-line Therapy for Metastatic Breast Cancer
Official Title: A Phase II Study of Tesetaxel as First-line Therapy for Subjects With Metastatic Breast Cancer
Study ID: NCT01221870
Brief Summary: The intravenously administered taxane, paclitaxel, is one of the most commonly employed agents for the treatment of both localized and advanced breast cancer. Tesetaxel is an orally administered taxane that is in development as first- and second-line treatment for patients with advanced cancers. This study is being undertaken to determine the efficacy and safety of tesetaxel administered as first-line therapy to patients with metastatic breast cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
The Moses H. Cone Regional Cancer Center, Greensboro, North Carolina, United States
The West Clinic, Memphis, Tennessee, United States
Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas, Texas, United States
Name: Andrew D Seidman, MD
Affiliation: Memorial Sloan Kettering Cancer Center
Role: PRINCIPAL_INVESTIGATOR