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Brief Title: Single Dose Ablative Radiation Treatment for Early-Stage Breast Cancer
Official Title: Single Dose Ablative Preoperative Radiation Treatment for Early-Stage Breast Cancer in Elderly Patients
Study ID: NCT02316561
Brief Summary: The purpose of the study is to investigate the feasibility of a preoperative, single dose, ablative partial breast radiation treatment in patients with early-stage breast cancer.
Detailed Description: A total of twenty-five patients will be treated with a single dose preoperative ablative radiation treatment. After a vigilant follow-up with MRI, breast conserving surgery will be performed 6 months after the ablative radiation treatment. The total follow-up time is 10 years. This study aims to present an ablative radiotherapy treatment approach that could resolve to some extent the disadvantages of current breast conserving treatment in elderly low-risk breast cancer patients who are currently not treated according to guidelines due to co-morbidity.
Minimum Age: 50 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
University Medical Center Utrecht, Utrecht, , Netherlands
Name: HJGD van den Bongard, MD, PhD
Affiliation: UMC Utrecht
Role: PRINCIPAL_INVESTIGATOR