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Brief Title: Preventing Chemotherapy-induced Peripheral Neuropathy Using PRESIONA Exercise Program
Official Title: Prevention of Chemotherapy-induced Peripheral Neuropathy With Therapeutic Exercise and Blood Flow Restriction Using PRESIONA Program
Study ID: NCT04652609
Brief Summary: The aim of this study is to determinate if therapeutic exercise with blood flow restriction (BFR) during neoadjuvant chemotherapy potentialy neurotoxic could prevent the onset of chemotherapy induced peripheral neuropathy (CIPN) comparing to usual care.
Detailed Description: CIPN is a side effect of cancer therapies that nowadays has no solution, so our intention is to carry out a preventive therapy against the onset of CIPN. The nature of the studies that try to prevent is very diverse, but one of the wide tools is therapeutic exercise. In this case we intend to combine therapeutic exercise with BFR to obtain a pre-conditioning effect that protects intraepidermal fibers from exposure to the chemotherapy.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
University of Granada, Granada, , Spain
Name: Irene Cantarero-Villanueva, PhD
Affiliation: Physical Therapy Deparment, Faculty of Health Sciences, University of Granada
Role: PRINCIPAL_INVESTIGATOR