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Brief Title: Randomized Study Evaluating Ixabepilone Plus Capecitabine or Docetaxel Plus Capecitabine in Metastatic Breast Cancer
Official Title: IXTEND: A Randomized Phase 2 Study to Evaluate the Combination of Ixabepilone Plus Capecitabine or Capecitabine Plus Docetaxel in the Treatment of Metastatic Breast Cancer
Study ID: NCT00546364
Brief Summary: The purpose of this study is to assess the effect of ixabepilone plus capecitabine or docetaxel plus capecitabine on shrinking or slowing the growth of metastatic breast cancer in women. The safety of this combination therapy will also be evaluated.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Dch Cancer Treatment Center, Tuscaloosa, Alabama, United States
Scripps Cancer Center, La Jolla, California, United States
Cancer Center of Central Connecticut, Southington, Connecticut, United States
Local Institution, Newark, Delaware, United States
Georgetown University Medical Center, Washington, District of Columbia, United States
Local Institution, Jacksonville, Florida, United States
Local Institution, Miami, Florida, United States
Medical Oncology Associates of Augusta, PC, Augusta, Georgia, United States
Local Institution, Honolulu, Hawaii, United States
Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
John W Kugler, MD, Peoria, Illinois, United States
Midwestern Regional Medical Center, Zion, Illinois, United States
Center for Cancer Care at Goshen Health System, Goshen, Indiana, United States
Monroe Medical Associates, Munster, Indiana, United States
Cancer Center of Kansas, Wichita, Kansas, United States
University of Kentucky, Lexington, Kentucky, United States
University Medical Center, Inc, Louisville, Kentucky, United States
Hematology/Oncology Clinic, Baton Rouge, Louisiana, United States
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States
Sinai Hospital of Baltimore, Baltimore, Maryland, United States
Center for Cancer & Blood Disorders, PC, Bethesda, Maryland, United States
Jackson Oncology Associates, Pllc, Jackson, Mississippi, United States
The Center for Cancer and Hematologic Disease, Cherry Hill, New Jersey, United States
The Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, United States
Howell Office Plaza, Howell, New Jersey, United States
Local Institution, Newark, New Jersey, United States
Cooper Hospital, Division of Hematology/Oncology, Voorhees, New Jersey, United States
UNM Cancer Center, Albuquerque, New Mexico, United States
New Mexico Cancer Care Associates (NMCCA), Santa Fe, New Mexico, United States
Arena Oncology Associates, PC, Lake Success, New York, United States
Hematology Oncology Associates of Rockland, Nyack, New York, United States
Gaston Hematology and Oncology, Gastonia, North Carolina, United States
Marion L Shepard Cancer Center, Washington, North Carolina, United States
Akron General Medical Center, Akron, Ohio, United States
Summa Health System, Akron, Ohio, United States
Local Institution, Canton, Ohio, United States
Mid Ohio Oncology/Hematology, Inc, dba The Mark H Zangmeister Center, Columbus, Ohio, United States
Doylestown Hospital, Doylestown, Pennsylvania, United States
Hematology & Oncology Associates of Nepa, Dunmore, Pennsylvania, United States
Regional Hematology Oncology, PC, Langhorne, Pennsylvania, United States
St Mary Medical Center, Langhorne, Pennsylvania, United States
Local Institution, Philadelphia, Pennsylvania, United States
Albert Einstein Cancer Center, Philadelphia, Pennsylvania, United States
Local Institution, Woonsocket, Rhode Island, United States
Charleston Cancer Center, Charleston, South Carolina, United States
Lowcountry Hematology & Oncology, PA, Mt Pleasant, South Carolina, United States
Santee Hematology/Oncology, Sumter, South Carolina, United States
Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota, United States
Kingsport Hematology Oncology, Kingsport, Tennessee, United States
The University of Tennessee Medical Center, Knoxville, Tennessee, United States
Austin Cancer Centers, Austin, Texas, United States
Cancer Specialists of South Texas, Corpus Christi, Texas, United States
Coastal Bend Cancer Center, Corpus Christi, Texas, United States
Edward L Middleman, MD, Duncanville, Texas, United States
Section Chief Medical Oncology, Houston, Texas, United States
Jose A Figueroa, MD, Lubbock, Texas, United States
Southlake Oncology, Southlake, Texas, United States
Peninsula Cancer Institute, Newport News, Virginia, United States
Providence Cancer Center, Spokane, Washington, United States
Leah L Dietrich, MD, La Crosse, Wisconsin, United States
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR