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Spots Global Cancer Trial Database for Weekly vs. Every 2 Week vs. Every 3 Week Administration of ABI-007 (Abraxane)/Bevacizumab Combination in Metastatic Breast Cancer

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Trial Identification

Brief Title: Weekly vs. Every 2 Week vs. Every 3 Week Administration of ABI-007 (Abraxane)/Bevacizumab Combination in Metastatic Breast Cancer

Official Title: A Phase II Study of Weekly Versus Every 2-week Versus Every 3-week Administration of ABI-007 (Abraxane) in Combination With Bevacizumab in Women With Metastatic Breast Cancer.

Study ID: NCT00281528

Study Description

Brief Summary: This is a multi-center, open-label, randomized Phase II study in previously untreated patients with metastatic breast cancer to evaluate the antitumor activity and safety of weekly dose-dense ABI-007 (Abraxane) compared to 2-weekly regimen vs the standard 3-weekly infusion. All patients will also receive concurrent bevacizumab.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Division of Hematology/Oncology University of Alabama at Birmingham, Birmingham, Alabama, United States

Little Rock Hematology Oncology Associates, Little Rock, Arkansas, United States

California Oncology of the Central Valley, Fresno, California, United States

Glendale Memorial Hospital & Health Center, Glendale, California, United States

Front Range Cancer Specialists, Fort Collins, Colorado, United States

Oncology Associates of Bridgeport, Bridgeport, Connecticut, United States

Palm Beach Institute of Hematology and Oncology, Boynton Beach, Florida, United States

Memorial Cancer Institute/Breast Cancer Center, Hollywood, Florida, United States

Florida Cancer Institute, Hudson, Florida, United States

Hematology Oncology Associates, Lake Worth, Florida, United States

Medical Specialist of the Palm Beaches, Inc, Lake Worth, Florida, United States

Gulfcoast Oncology Associates, Saint Petersburg, Florida, United States

Peachtree Hematology & Oncology Associates, Atlanta, Georgia, United States

Northwest Georgia Oncology Centers, PC, Marietta, Georgia, United States

Center of Hope for Cancers and Blood, Stockbridge, Georgia, United States

Maine Center for Cancer Medicine & Blood Disorders, Scarborough, Maine, United States

Greater Baltimore Medical Center, Baltimore, Maryland, United States

Harbor View Cancer Center, Baltimore, Maryland, United States

Boston Medical Center Moakley Building, Solomont Center for Hematology & Medical Oncology, Boston, Massachusetts, United States

North Shore Medical Cancer Center, Peabody, Massachusetts, United States

St. John's Mercy Medical Center, Saint Louis, Missouri, United States

Nebraska Methodist Hospital, Omaha, Nebraska, United States

Drs. Forte, Schleidere, & Attas, PA, Englewood, New Jersey, United States

Saint Barnabas Medical Center, Livingston, New Jersey, United States

Monmouth Medical Center, Long Branch, New Jersey, United States

Rosewell Park Cancer Institute Elm & Carlton Carlton Building, Buffalo, New York, United States

Beth Israel Comprehensive Cancer Center, New York, New York, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

NYU Clinical Cancer Center, New York, New York, United States

Marion L. Shepard Cancer Center, Washington, North Carolina, United States

Medical Oncology Aultman Hospital, Canton, Ohio, United States

Cancer Centers of Southwest Oklahoma Research, Lawton, Oklahoma, United States

Abington Hematology Oncology, Willow Grove, Pennsylvania, United States

Family Cancer Center, Collierville, Tennessee, United States

Tennessee Cancer Specialists, Knoxville, Tennessee, United States

TX Oncology, PA, Austin, Texas, United States

South Texas Oncology & Hematology Clinical Research Dept., San Antonio, Texas, United States

Virginia Commonwealth University Medical Oncology, Richmond, Virginia, United States

Swedish Cancer Institute, Seattle, Washington, United States

Metropolitan Oncology Center, San Juan, , Puerto Rico

Contact Details

Name: Andrew Seidman, MD

Affiliation: Memorial Sloan Kettering Cancer Center

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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