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Brief Title: A Study of Lapatinib in Combination With Everolimus in Patients With Advanced, Triple Negative Breast Cancer
Official Title: Phase II Trial of Lapatinib in Combination With Everolimus in Triple Negative Metastatic or Locally Advanced Breast Cancer
Study ID: NCT01272141
Brief Summary: The patient is being asked to join this clinical research study to find out if lapatinib, an agent that targets a protein, called epidermal growth factor receptor (EGFR) on the surface of cancer cells in combination with everolimus, an agent that targets a protein in the cancer cell, called mammalian target of rapamycin (mTOR) is effective in metastatic triple negative breast cancers that are no longer controlled by standard chemotherapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Grady Memorial Hospital, Atlanta, Georgia, United States
Emory Midtown (Crawford Long Hospital), Atlanta, Georgia, United States
Emory University Winship Cancer Institute, Atlanta, Georgia, United States
Name: William Read, MD
Affiliation: Emory University Winship Cancer Institute
Role: PRINCIPAL_INVESTIGATOR