Spots Global Cancer Trial Database for A Study of Pertuzumab in Combination With Trastuzumab (Herceptin) and a Taxane in First-Line Treatment in Participants With Human Epidermal Growth Factor 2 (HER2)-Positive Advanced Breast Cancer
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Trial Identification
Brief Title: A Study of Pertuzumab in Combination With Trastuzumab (Herceptin) and a Taxane in First-Line Treatment in Participants With Human Epidermal Growth Factor 2 (HER2)-Positive Advanced Breast Cancer
Official Title: A Multicenter, Open-Label, Single-Arm Study of Pertuzumab in Combination With Trastuzumab and a Taxane in First Line Treatment of Patients With HER2-Positive Advanced (Metastatic or Locally Recurrent) Breast Cancer
Study ID: NCT01572038
Conditions
Study Description
Brief Summary: This multicenter, open-label, single-arm, Phase IIIb study will evaluate the safety and tolerability of pertuzumab in combination with trastuzumab (Herceptin) and a taxane (docetaxel, paclitaxel or nab-paclitaxel) in first-line treatment in participants with metastatic or locally recurrent HER2-positive breast cancer. Participants will receive pertuzumab intravenously (IV) and trastuzumab (Herceptin) IV plus a taxane in cycles of 3 weeks each until predefined study end, unacceptable toxicity, withdrawal of consent, disease progression, or death, whichever occurs first.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
CPMC; Service d'Oncologie Médicale, Algiers, , Algeria
Centro Oncologico Riojano Integral (CORI), La Rioja, , Argentina
Instituto de Oncología de Rosario, Rosario, , Argentina
Canberra Hospital; Medical Oncology, Canberra, Australian Capital Territory, Australia
Royal Prince Alfred Hospital; Medical Oncology, Camperdown, New South Wales, Australia
HOCA Chermside, Chermside, Queensland, Australia
Mater Hospital; Cancer Services, South Brisbane, Queensland, Australia
Austin and Repatriation Medical Centre; Cancer Services, Melbourne, Victoria, Australia
Royal Melbourne Hospital; Hematology and Medical Oncology, Parkville, Victoria, Australia
Lkh-Univ. Klinikum Graz; Klinik Für Gynäkologie, Graz, , Austria
LKH-UNIV. KLINIKUM GRAZ; Klinische Abteilung für Onkologie, Graz, , Austria
Tiroler Landeskrankenanstalten Ges.M.B.H.; Abt. Für Gynäkologie, Innsbruck, , Austria
Ordensklinikum Linz Barmherzige Schwestern; Abt. fur Innere Medizin 1, Linz, , Austria
Lkh Salzburg - Univ. Klinikum Salzburg; Iii. Medizinische Abt., Salzburg, , Austria
A.Ö. Lhk; Ii. Medizinische Abt. Mit Schwerpunkt Gaströnter. & Onkologie, Steyr, , Austria
Medizinische Universität Wien; Univ.Klinik für Frauenheilkunde - Klinik für Gynäkologie, Wien, , Austria
Medizinische Universität Wien; Univ.Klinik für Innere Medizin I - Abt. für Onkologie, Wien, , Austria
UZ Brussel, Brussel, , Belgium
UZ Antwerpen, Edegem, , Belgium
UZ Gent, Gent, , Belgium
UZ Leuven Gasthuisberg, Leuven, , Belgium
CHU Sart-Tilman, Liège, , Belgium
Oncologistas Associados, Rio de Janeiro, RJ, Brazil
Hospital Sao Lucas - PUCRS, Porto Alegre, RS, Brazil
Hospital Amaral Carvalho, Jau, SP, Brazil
Hospital Sirio Libanes; Centro de Oncologia, Sao Paulo, SP, Brazil
Hospital Perola Byington, Sao Paulo, SP, Brazil
Hospital das Clinicas - FMUSP, Sao Paulo, SP, Brazil
Hospital Sao Jose, São Paulo, SP, Brazil
Cross Cancer Institute ; Dept of Medical Oncology, Edmonton, Alberta, Canada
Lions Gate Hospital, North Vancouver, British Columbia, Canada
Bcca - Vancouver Island Cancer Centre; Oncology, Victoria, British Columbia, Canada
Queen Elizabeth II Health Sciences Centre; Oncology, Halifax, Nova Scotia, Canada
William Osler Health System Brampton Civic Hospital, Brampton, Ontario, Canada
Grand River Hospital, Kitchener, Ontario, Canada
Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada
CSSS champlain - Charles-Le Moyne, Greenfield Park, Quebec, Canada
Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada
McGill University; Sir Mortimer B Davis Jewish General Hospital; Oncology, Montreal, Quebec, Canada
Beijing Cancer Hospital, Beijing, , China
Southwest Hospital , Third Military Medical University, Chongqing, , China
Sun Yet-sen University Cancer Center, Guangzhou, , China
Heilongjiang Provincial Tumor Hospital, Harbin, , China
Jiangsu Cancer Hospital, Nanjing, , China
Fudan University Shanghai Cancer Center, Shanghai, , China
Tianjin Cancer Hospital, Tianjin, , China
The First Affiliated Hospital of The Fourth Military Medical University (Xijing Hospital), Xi'an, , China
First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, , China
Hospital Solca Portoviejo; Oncologia, Portoviejo, , Ecuador
Hospital Solca Quito; Oncologia, Quito, , Ecuador
Manial Specialized Hospital; Oncology, Cairo, , Egypt
El Mokatam HIO Hospital, Cairo, , Egypt
Nci; Oncology Dept, Cairo, , Egypt
North Estonia Medical Centre Foundation; Oncology Center, Tallinn, , Estonia
Tartu University Hospital; Clinic of Hematology and Oncology, Tartu, , Estonia
Helsinki University Central Hospital; Oncology Clinics, Helsinki, , Finland
Satakunta Central Hospital; Oncology, Pori, , Finland
Tampere University Hospital; Dept of Oncology, Tampere, , Finland
Turku Uni Central Hospital; Oncology Clinics, Turku, , Finland
Clinique De L Europe; Radiotherapie Chimiotherapie, Amiens, , France
ICO Paul Papin; Oncologie Medicale., Angers, , France
Polyclinique Bordeaux Nord Aquitaine; Chimiotherapie Radiotherapie, Bordeaux, , France
Centre Hospitalier Fleyriat; Oncologie/Hematologie, Bourg En Bresse, , France
Centre Leonard De Vinci;Chimiotherapie, Dechy, , France
Fondation Clement Drevon; Oncology, Dijon, , France
Centre Georges Francois Leclerc; Oncologie 3, Dijon, , France
Clinique Sainte Marguerite; Oncologie Medicale, Hyeres, , France
Polyclinique de Blois; Chimiotherapie Ambulatoire, La Chaussee St Victor, , France
Clinique Victor Hugo, LeMans, , France
Polyclinique Du Bois; Centre Bourgogne, Lille, , France
Clinique Chenieux; Oncology, Limoges, , France
Centre Leon Berard; Departement Oncologie Medicale, Lyon, , France
Institut Paoli Calmettes; Oncologie Medicale, Marseille, , France
Centre Azureen De Cancerologie; Cons externes, Mougins, , France
Hopital Cochin; Unite Fonctionnelle D Oncologie, Paris, , France
Hopital Hotel Dieu; Oncologie Medicale, Paris, , France
Institut Curie; Oncologie Medicale, Paris, , France
Hopital Saint Louis; Service Onco Thoracique, Paris, , France
Centre Catalan D' Oncologie, Perpignan, , France
Polyclinique De Courlancy; Centre Radiotherapie Oncologie, Reims, , France
Centre Eugene Marquis; Unite Huguenin, Rennes, , France
Centre Rene Huguenin; ONCOLOGIE GENETIQUE, Saint Cloud, , France
Chp Saint Gregoire; Cancerologie Radiotherapie, Saint Gregoire, , France
Ico Rene Gauducheau; Oncologie, Saint Herblain, , France
Institut D Oncologie Medical, Strasbourg, , France
Institut Claudius Regaud; Departement Oncologie Medicale, Toulouse, , France
Hopital Prive Drome Ardeche; Hopital De Jour, Valence, , France
Clinique Onco Des Dentellieres; Chimiotherapie Radiotherapie, Valenciennes, , France
Klinikum am Bruderwald; Frauenklinik, Bamberg, , Germany
Gynaekologicum Bremen; Prof. Dr. Willibald Schröder, Bremen, , Germany
Universitätsklinikum Erlangen; Frauenklinik, Erlangen, , Germany
Universitätsklinikum Essen; Zentrum Für Frauenheilkunde, Essen, , Germany
Klinikum Esslingen; Klinik für Frauenheilkunde und Geburtshilfe, Esslingen, , Germany
AGAPLESION Markus-Krankenhaus, Frankfurt, , Germany
SRH Wald-Klinikum Gera; Klinik für Frauenheilkunde und Geburtshilfe, Gera, , Germany
Universitätsklinikum Hamburg-Eppendorf; Frauenklinik, Hamburg, , Germany
Gynaekologisch-Onkologische Schwerpunktpraxis Prof. Dr. med. Lueck, Dr. Schrader und Dr. Noeding, Hannover, , Germany
Nationales Centrum für Tumorerkrankungen (NCT) ; Gyn. Onk. Frauenklinik; Uniklinikum Heidelberg, Heidelberg, , Germany
Universitätsklinikum des Saarlandes; Klinik f. Frauenheilkunden und Geburtshilfe, Homburg/Saar, , Germany
St.-Vincenz-Krankenhaus; Frauenklinik, Limburg, , Germany
Universitätsklinikum Schleswig-Holstein / Campus Lübeck; Klinik für Frauenheilkunde und Geburtshilfe, Lübeck, , Germany
Brustzentrum Rhein-Ruhr Servicegesellschaft mbH, Mönchengladbach, , Germany
Klinikum rechts der Isar der TU München; Klinik und Poliklinik für Frauenheilkunde, München, , Germany
Ruppiner Kliniken, Klinik fuer Gynaekologie und Geburtshilfe, Neuruppin, , Germany
Agaplesion Diakonieklinikum Rotenburg, Rotenburg/Wümme, , Germany
Praxis Dr. Wagner, Saarbruecken, , Germany
Kreiskrankenhaus Torgau; Abt.Gynäkologie und Geburtshilfe, Torgau, , Germany
Universitätsklinik Tübingen; Frauenklinik, Tübingen, , Germany
Anticancer Hospital Ag. Savas ; 2Nd Dept. of Oncology - Internal Medicine, Athens, , Greece
University General Hospital of Heraklion, Crete, , Greece
University Hospital of Patras Medical Oncology, Patras, , Greece
Euromedical General Clinic of Thessaloniki; Oncology Department, Thessaloniki, , Greece
Papageorgiou General Hospital; Medical Oncology, Thessaloniki, , Greece
Hippokratio Hospital; 2Nd Internal Medicine, Αθηνα, , Greece
University Hospital of Larissa; Oncology, Λαρισα, , Greece
Queen Elizabeth Hospital; Clinical Oncology, Hong Kong, , Hong Kong
Szent Margit Hospital; Dept. of Oncology, Budapest, , Hungary
Fovarosi Szent Laszlo Korhaz-Rendelointezet; Onkologiai Osztaly X, Budapest, , Hungary
Orszagos Onkologial Intezet; Onkologiai Osztaly X, Budapest, , Hungary
Debreceni Egyetem Klinikai Kozpont ; Department of Oncology, Debrecen, , Hungary
Borsod-Abauj-Zemplen Megyei Korhaz Es Egyetemi Oktato Korhaz; Onkologiai Osztaly, Miskolc, , Hungary
Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika, Szeged, , Hungary
Soroka Medical Center; Oncology Dept, Beer Sheva, , Israel
Rambam Medical Center; Oncology, Haifa, , Israel
Wolfson Hospital; Oncology, Holon, , Israel
Shaare Zedek Medical Center; Oncology Dept, Jerusalem, , Israel
Hadassah Ein Karem Hospital; Oncology Dept, Jerusalem, , Israel
Nahariya Hospital; Oncology, Nahariya, , Israel
Rabin Medical Center; Oncology Dept, Petach Tikva, , Israel
Chaim Sheba Medical Center; Oncology Dept, Ramat Gan, , Israel
Kaplan Medical Center; Oncology Inst., Rehovot, , Israel
Sourasky / Ichilov Hospital; Dept. of Oncology, Tel Aviv, , Israel
Assuta Medical Centre; Oncology, Tel Aviv, , Israel
Assaf Harofeh; Oncology, Zerifin, , Israel
Azienda Ospedaliera San Giuseppe Moscati, Avellino, Campania, Italy
Az. Osp. Ospedale Civile; U.O. Di Oncologia Medica Ed Ematologia, Piacenza, Emilia-Romagna, Italy
Azienda USL di Ravenna; Unità Operativa di Oncologia Medica, Ravenna, Emilia-Romagna, Italy
Azienda Ospedaliero-Universitaria Dipartimento Interaziendale Di Oncologia, Udine, Friuli-Venezia Giulia, Italy
Ospedale Belcolle Di Viterbo; Oncologia, Viterbo, Lazio, Italy
Ente Ospedaliero Ospedali Galliera; S.C. Oncologia Medica, Genova, Liguria, Italy
Asst Papa Giovanni XXIII; Oncologia Medica, Bergamo, Lombardia, Italy
Ospedale Mater Salutis; Dept of Oncology, Legnago, Lombardia, Italy
Irccs Ospedale San Raffaele;Oncologia Medica, Milano, Lombardia, Italy
Istituto Europeo Di Oncologia, Milano, Lombardia, Italy
Irccs Policlinico S. Matteo - Uni Pavia; Clinica Medica I Div. Med. Int. Onc. Medica E Gastroent., Pavia, Lombardia, Italy
Ospedali Riuniti Di Ancona; Oncology, Ancona, Marche, Italy
Ospedale Di Macerata; Oncologia, Macerata, Marche, Italy
Ospedale Maggiore Della Carita; Oncologia Medica, Novara, Piemonte, Italy
Ospedale Degli Infermi Di Biella; Reparto Oncologia Medica, Ponderano (BI), Piemonte, Italy
Fondazione Del Piemonte; Medical Oncology, Torino, Piemonte, Italy
Ospedale S. Vincenzo; Oncologia Medica, Taormina, Sicilia, Italy
Azienda Ospedaliero-Universitaria Careggi;S.C. Oncologia Medica 1, Firenze, Toscana, Italy
Arcispedale S.Anna; Oncologia Medica, Cona (Ferrara), Veneto, Italy
American University of Beirut - Medical Center, Beirut, , Lebanon
Hotel Dieu de France; Oncology, Beirut, , Lebanon
Hospital of Lithuanian University of Health. Sciences Kaunas Clinics, Kaunas, , Lithuania
Uni Oncology Inst. ; Chemo - Radiation Dept, Vilnius, , Lithuania
Iem-Fucam, D.f., , Mexico
Medica Sur Centro Oncologico Integral, D.f., , Mexico
Instituto Nacional de Cancerologia; Oncology, Distrito Federal, , Mexico
Consultorio de Medicina Especializada; Dentro de Condominio San Francisco, Mexico City, , Mexico
Centro Medico Nacional Siglo Xxi - Imss; Hospital de Oncologia, Mexico City, , Mexico
Instituto Nacional de Ciencias Médicas Y de La Nutricion Zubirán, Mexico City, , Mexico
Hospital General de México; Unidad de Oncologia, Mexico DF, , Mexico
Cancerologia de Queretaro; Oncologia, Queretaro, Queretaro, , Mexico
Institut National D'oncologie Sidi Mohammed Ben Abdellah; Anatomopathologie, Rabat, , Morocco
Medisch Centrum Alkmaar, Alkmaar, , Netherlands
Albert Schweitzer Ziekenhuis, Dordrecht, , Netherlands
Catharina ZKHS; Inwendige Geneeskunde Afd., Eindhoven, , Netherlands
Martini Ziekenhuis; Dept of Internal Medicine, Groningen, , Netherlands
Mc Haaglanden, Locatie Antoniushove; Interne Geneeskunde, Leidschendam, , Netherlands
Ikazia Ziekenhuis; Interne Oncologie, Rotterdam, , Netherlands
Twee Steden Ziekenhuis - Locatie Tilburg; Interne Geneesekunde, Tilburg, , Netherlands
Vie Curie, Venlo, , Netherlands
Shifa International Hospital; Department of Oncology, Islamabad, , Pakistan
Shaukat Khanum Memorial Cancer Hospital; Department of Oncology, Lahore, , Pakistan
Hameed Latif Hospital; Department of Oncology, Lahore, , Pakistan
Instituto;Oncologico Miraflores, Lima, , Peru
Clinica Internacional, Sede San Borja; Unidad de Investigacion de Clínica Internacional, Lima, , Peru
Hospital Nacional LNS dela Policia Nacional del Perú. Unidad Onco; Deapartamento de Oncología, Lima, , Peru
Bialostockie Centrum Onkologii; Oddzial Onkologii Klinicznej, Bialystok, , Poland
Świętokrzyskie Centrum Onkologii; Dział Chemioterapii, Kielce, , Poland
Szpital Uniwersytecki w Krakowie, Oddział Kliniczny Kliniki Onkologii, Kraków, , Poland
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii; Poradnia Chemioterapii, Lodz, , Poland
Europejskie Centrum Zdrowia Otwock Szpital im. Fryderyka Chopina, Klinika Onkologii, Otwock, , Poland
Cent.Onkologii-Instytut im. M. S-Curie, Klinika Now. Piersi i Chirurgii Rekon, Warszawa, , Poland
IPO de Coimbra; Servico de Oncologia Medica, Coimbra, , Portugal
Hospital do Espirito Santo; Servico de Oncologia Medica, Evora, , Portugal
Centro Clinico Champalimaud; Oncologia Medica, Lisboa, , Portugal
Hospital da Luz; Departamento de Oncologia Medica, Lisboa, , Portugal
Hospital de Santa Maria; Servico de Oncologia Medica, Lisboa, , Portugal
Hospital Beatriz Angelo; Departamento de Oncologia, Loures, , Portugal
IPO do Porto; Servico de Oncologia Medica, Porto, , Portugal
Hospital de Sao Joao; Servico de Oncologia, Porto, , Portugal
King Faisal Specialist Hospital & Research Centre; Oncology, Riyadh, , Saudi Arabia
King Abdul Aziz Medical City, King Fahd National Guard; Oncology, Riyadh, , Saudi Arabia
Institute for Onc/Rad Serbia, Belgrade, , Serbia
Oncology Institute of Vojvodina, Sremska Kamenica, , Serbia
Institute of Oncology Ljubljana, Ljubljana, , Slovenia
Hospital Virgen de los Lirios; Servicio de Oncologia, Alcoy, Alicante, Spain
Hospital General de Elda; Servicio de Oncologia, Elda, Alicante, Spain
Hospital de Cabueñes; Servicio de Oncologia, Gijon, Asturias, Spain
Corporacio Sanitaria Parc Tauli; Servicio de Oncologia, Sabadell, Barcelona, Spain
Hospital de Jerez de la Frontera; Servicio de Oncologia, Jerez de La Frontera, Cadiz, Spain
Hospital Provincial de Castellon; Servicio de Oncologia, Castellon de La Plana, Castellon, Spain
Hospital de Barbastro; Servicio de Oncologia, Barbastro, Huesca, Spain
Hospital Universitario Son Espases, Palma De Mallorca, Islas Baleares, Spain
Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia, Santiago de Compostela, LA Coruña, Spain
Complejo Hospitalario San Millan - San Pedro; Servicio de Oncologia, Logroño, LA Rioja, Spain
Hospital Universitario Materno Infantil de Gran Canaria; Servicio de Oncologia, Las Palmas de Gran Canaria, LAS Palmas, Spain
Hospital de Gran Canaria Dr. Negrin; Servicio de Oncologia, Las Palmas de Gran Canaria, LAS Palmas, Spain
Fundacion Hospital de Alcorcon; Servicio de Oncologia, Alcorcon, Madrid, Spain
Hospital Severo Ochoa; Servicio de Oncologia, Leganes, Madrid, Spain
Clinica Universitaria de Navarra; Servicio de Oncologia, Pamplona, Navarra, Spain
Hospital Universitari Sant Joan de Reus; Servicio de Oncologia, Reus, Tarragona, Spain
Complejo Hospitalario Nuestra Señora de la Candelaria; Servicio de Oncologia, Santa Cruz de Tenerife, Tenerife, Spain
Hospital de Sagunto; Servicio de Oncologia, Sagunto, Valencia, Spain
Hospital de Basurto; Servicio de Oncologia, Bilbao, Vizcaya, Spain
Hospital Quiron Barcelona; Servicio de Oncologia, Barcelona, , Spain
Hospital Clínic i Provincial; Servicio de Hematología y Oncología, Barcelona, , Spain
Hospital de la Santa Creu i Sant Pau; Servicio de Oncologia, Barcelona, , Spain
Complejo Asistencial Universitario De Burgos; Servicio de Oncologia, Burgos, , Spain
Hospital San Pedro De Alcantara; Servicio de Oncologia, Caceres, , Spain
Hospital Universitari de Girona Dr. Josep Trueta; Servicio de Oncologia, Girona, , Spain
Hospital Universitario Virgen de las Nieves; Servicio de Oncologia, Granada, , Spain
Hospital General Universitario de Guadalajara; Servicio de Oncologia, Guadalajara, , Spain
Complejo Asistencial Universitario de Leon; Servicio de Oncologia, Leon, , Spain
Centro Oncologico MD Anderson Internacional; Servicio de Oncologia, Madrid, , Spain
Hospital Ramon y Cajal; Servicio de Oncologia, Madrid, , Spain
Fundacion Jimenez Diaz; Servicio de Oncologia, Madrid, , Spain
Hospital Universitario Clínico San Carlos; Servicio de Oncologia, Madrid, , Spain
Hospital Universitario 12 de Octubre; Servicio de Oncologia, Madrid, , Spain
Hospital Universitario La Paz; Servicio de Oncologia, Madrid, , Spain
HOSPITAL DE MADRID NORTE SANCHINARRO- CENTRO INTEGRAL ONCOLOGICO CLARA CAMPAL; Servicio de Oncologia, Madrid, , Spain
Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia, Malaga, , Spain
Hospital General Universitario J.M Morales Meseguer; Servicio de Oncologia, Murcia, , Spain
Hospital Universitario Virgen de Arrixaca; Servicio de Oncologia, Murcia, , Spain
Hospital de Navarra; Servicio de Oncologia, Navarra, , Spain
Complejo Hospitalario de Orense; Servicio de Oncologia, Orense, , Spain
Hospital Clinico Universitario de Salamanca; Servicio de Oncologia, Salamanca, , Spain
Hospital Universitario Virgen Macarena; Servicio de Oncologia, Sevilla, , Spain
Hospital Arnau de Vilanova (Valencia) Servicio de Oncologia, Valencia, , Spain
Hospital Universitario Dr. Peset, Valencia, , Spain
Hospital Clinico Universitario de Valladolid; Servicio de Oncologia, Valladolid, , Spain
Hospital de Rio Hortega; Servicio de Oncologia, Valladolid, , Spain
Hospital Clinico Universitario Lozano Blesa; Servicio de Oncologia, Zaragoza, , Spain
Hospital Universitario Miguel Servet; Servicio Oncologia, Zaragoza, , Spain
Gävle Sjukhus; Onkologiska Kliniken, Gävle, , Sweden
Sahlgrenska Universitetssjukhuset; Jubileumskliniken, Göteborg, , Sweden
Centralsjukhuset Karlstad, Onkologkliniken, Karlstad, , Sweden
Skånes University Hospital, Skånes Department of Onclology, Lund, , Sweden
Centrallasarettet Växjö, Onkologkliniken, Vaxjo, , Sweden
Västmanlands sjukhus Västerås, Onkologkliniken, Västerås, , Sweden
Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology, Adana, , Turkey
Akdeniz University Medical Faculty; Medical Oncology Department, Antalya, , Turkey
Ege University Medical Faculty; Medical Oncology Department, Bornova, İ̇zmi̇r, , Turkey
Trakya University Medical Faculty Research And Practice Hospital Medical Oncology Department, Edirne, , Turkey
Hacettepe Uni Medical Faculty Hospital; Oncology Dept, Sihhiye/Ankara, , Turkey
Mun. Multifield Clin.Hosp.#4,Dept. of Chemotherapy, DSMU; Chair of Oncology and Medical Radiology, Dnipropetrovsk, , Ukraine
Kyiv City Clinical Oncological Center; Chemotherapy Department, Kiev, , Ukraine
State Oncology Regional Treatment-Diagnostic Center; Chemotherapy Department, Lviv, , Ukraine
Zaporozhye Regional Oncology Hospital; Dept of Oncology, Zaporozhye, , Ukraine
Tawam Hospital, Al Ain, , United Arab Emirates
Royal United Hospital; Oncology Department, Bath, , United Kingdom
City Hospital NHS Trust, Birmingham, , United Kingdom
Bristol Haematology and Oncology Centre, Bristol, , United Kingdom
Addenbrookes Hospital; Dept of Oncology, Cambridge, , United Kingdom
Velindre Hospital, Cardiff, , United Kingdom
Walsgrave Hospital, Coventry, , United Kingdom
Royal Derby Hospital, Derby, , United Kingdom
University Hospital of North Durham, Durham, , United Kingdom
Hairmyres Hospital; Oncology Dept, East Kilbride, , United Kingdom
Eastbourne District Hospital; Department of Pharmacy, Eastbourne, , United Kingdom
Beatson West of Scotland Cancer Centre, Glasgow, , United Kingdom
Diana Princess of Wales Hosp., Grimsby, , United Kingdom
Royal Surrey County Hospital, Guildford, , United Kingdom
Leeds Teaching Hosp NHS Trust;St James's Institute of Onc, Leeds, , United Kingdom
Huddersfield Royal Infirmary - Pharmacy department, Lindley, , United Kingdom
Barts and the London NHS Trust., London, , United Kingdom
Royal Free Hospital; Dept of Oncology, London, , United Kingdom
Kings College Hospital NHS Foundation Trust, London, , United Kingdom
Royal Marsden Hospital - London, London, , United Kingdom
Macclesfield District General Hospital, Macclesfield, , United Kingdom
Christie Hospital; Breast Cancer Research Office, Manchester, , United Kingdom
James Cook Uni Hospital, Middlesborough, , United Kingdom
Freeman Hospital; Northern Centre For Cancer Care, New Castle Upon Tyne, , United Kingdom
Mount Vernon Cancer Centre, Northwood, , United Kingdom
Churchill Hospital, Oxford, , United Kingdom
Peterborough City Hospital, Peterborough, , United Kingdom
Derriford Hospital; Plymouth Oncology Centre, Plymouth, , United Kingdom
Musgrove Park Hospital, Somerset, , United Kingdom
The Royal Marsden Hospital, Sutton, , United Kingdom
Royal Cornwall Hospital, Truro, , United Kingdom
Wishaw General Hospital, Wishaw, , United Kingdom
Grupo Oncológico Cooperativo Uruguayo; Hospital de Clínicas - Dpto. de Oncología, Montevideo, , Uruguay
Hospital Central De Las FF.AA.; Servicio De Oncologia, Montevideo, , Uruguay
Hospital Pereira Rossell; Oncology Department, Montevideo, , Uruguay
Centro Integral de Oncología, Caracas, , Venezuela
Centro Médico Docente La Trinidad; Servicio de Gastroenterología, Caracas, , Venezuela
Contact Details
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR
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