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Brief Title: Randomized Trial Of Exemestane Versus Continued Tamoxifen In Postmenopausal Women With Early Breast Cancer
Official Title: Randomized Double-Blind Trial In Postmenopausal Women With Primary Breast Cancer Who Have Received Adjuvant Tamoxifen For 2-3 Years, Comparing Subsequent Adjuvant Exemestane Treatment With Further Tamoxifen
Study ID: NCT00038467
Brief Summary: To compare the sequential administration of exemestane with administration of further tamoxifen until 5 years in postmenopausal women with operable breast cancer who have already received 2-3 years of adjuvant tamoxifen, in terms of disease-free survival (DFS), overall survival (OS), incidence of contralateral breast cancer and long-term tolerability.
Detailed Description:
Minimum Age: 30 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Pfizer Investigational Site, Birmingham, Alabama, United States
Pfizer Investigational Site, Birmingham, Alabama, United States
Pfizer Investigational Site, Birmingham, Alabama, United States
Pfizer Investigational Site, Green Valley, Arizona, United States
Pfizer Investigational Site, Green Velley, Arizona, United States
Pfizer Investigational Site, Tucson, Arizona, United States
Pfizer Investigational Site, Tucson, Arizona, United States
Pfizer Investigational Site, Tucson, Arizona, United States
Pfizer Investigational Site, Tucson, Arizona, United States
Pfizer Investigational Site, Tucson, Arizona, United States
Pfizer Investigational Site, Boulder, Colorado, United States
Pfizer Investigational Site, Colorado Springs, Colorado, United States
Pfizer Investigational Site, Denver, Colorado, United States
Pfizer Investigational Site, Fort Collins, Colorado, United States
Pfizer Investigational Site, Lakewood, Colorado, United States
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Pfizer Investigational Site, Jacksonville Beach, Florida, United States
Pfizer Investigational Site, Jacksonville, Florida, United States
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Pfizer Investigational Site, Ocala, Florida, United States
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Pfizer Investigational Site, Fishers, Indiana, United States
Pfizer Investigational Site, Fishers, Indiana, United States
Pfizer Investigational Site, Indianapolis, Indiana, United States
Pfizer Investigational Site, Indianapolis, Indiana, United States
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Pfizer Investigational Site, Cedar Rapids, Iowa, United States
Pfizer Investigational Site, Pittsfield, Massachusetts, United States
Pfizer Investigational Site, Albany, New York, United States
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Pfizer Investigational Site, Portland, Oregon, United States
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Pfizer Investigational Site, Arlington, Texas, United States
Pfizer Investigational Site, Bedford, Texas, United States
Pfizer Investigational Site, Dallas, Texas, United States
Pfizer Investigational Site, Dallas, Texas, United States
Pfizer Investigational Site, Dallas, Texas, United States
Pfizer Investigational Site, El Paso, Texas, United States
Pfizer Investigational Site, El Paso, Texas, United States
Pfizer Investigational Site, Garland, Texas, United States
Pfizer Investigational Site, Houston, Texas, United States
Pfizer Investigational Site, Houston, Texas, United States
Pfizer Investigational Site, Houston, Texas, United States
Pfizer Investigational Site, Houston, Texas, United States
Pfizer Investigational Site, Longview, Texas, United States
Pfizer Investigational Site, McAllen, Texas, United States
Pfizer Investigational Site, Mesquite, Texas, United States
Pfizer Investigational Site, Odessa, Texas, United States
Pfizer Investigational Site, Pasadena, Texas, United States
Pfizer Investigational Site, Plano, Texas, United States
Pfizer Investigational Site, San Antonio, Texas, United States
Pfizer Investigational Site, Sherman, Texas, United States
Pfizer Investigational Site, Sugar Land, Texas, United States
Pfizer Investigational Site, Tyler, Texas, United States
Pfizer Investigational Site, Weslaco, Texas, United States
Pfizer Investigational Site, Spokane, Washington, United States
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Pfizer Investigational Site, Haedo, Buenos Aires, Argentina
Pfizer Investigational Site, San Isidro, Buenos Aires, Argentina
Pfizer Investigational Site, San Martin, Buenos Aires, Argentina
Pfizer Investigational Site, Buenos Aires, Capital Federal, Argentina
Pfizer Investigational Site, Buenos Aires, Capital Federal, Argentina
Pfizer Investigational Site, Buenos Aires, Capital Federal, Argentina
Pfizer Investigational Site, Buenos Aires, Capital Federal, Argentina
Pfizer Investigational Site, Buenos Aires, Capital Federal, Argentina
Pfizer Investigational Site, Rosario 2000, Pcia. de Santa Fe, Argentina
Pfizer Investigational Site, Rosario, Santa Fe, Argentina
Pfizer Investigational Site, Buenos Aires, , Argentina
Pfizer Investigational Site, Cordoba, , Argentina
Pfizer Investigational Site, Camperdown, New South Wales, Australia
Pfizer Investigational Site, Dubbo, New South Wales, Australia
Pfizer Investigational Site, Liverpool, New South Wales, Australia
Pfizer Investigational Site, Waratah, New South Wales, Australia
Pfizer Investigational Site, Adelaide, South Australia, Australia
Pfizer Investigational Site, Bendigo, Victoria, Australia
Pfizer Investigational Site, Box Hill, Victoria, Australia
Pfizer Investigational Site, Ringwood East, Victoria, Australia
Pfizer Investigational Site, Antwerpen, , Belgium
Pfizer Investigational Site, Arlon, , Belgium
Pfizer Investigational Site, Baudour, , Belgium
Pfizer Investigational Site, Brasschaat, , Belgium
Pfizer Investigational Site, Bruxelles, , Belgium
Pfizer Investigational Site, Bruxelles, , Belgium
Pfizer Investigational Site, Charleroi, , Belgium
Pfizer Investigational Site, Edegem, , Belgium
Pfizer Investigational Site, Genk, , Belgium
Pfizer Investigational Site, Haine St. Paul, , Belgium
Pfizer Investigational Site, Hasselt, , Belgium
Pfizer Investigational Site, Kraainem, , Belgium
Pfizer Investigational Site, La Louviere, , Belgium
Pfizer Investigational Site, Leuven, , Belgium
Pfizer Investigational Site, Liege, , Belgium
Pfizer Investigational Site, Merksem, , Belgium
Pfizer Investigational Site, Namur, , Belgium
Pfizer Investigational Site, Verviers, , Belgium
Pfizer Investigational Site, Wilrijk, , Belgium
Pfizer Investigational Site, Sarajevo, , Bosnia and Herzegovina
Pfizer Investigational Site, Plovdiv, , Bulgaria
Pfizer Investigational Site, Sofia, , Bulgaria
Pfizer Investigational Site, Sofia, , Bulgaria
Pfizer Investigational Site, Sofia, , Bulgaria
Pfizer Investigational Site, Stara Zagora, , Bulgaria
Pfizer Investigational Site, Osijek, , Croatia
Pfizer Investigational Site, Split, , Croatia
Pfizer Investigational Site, Zagreb, , Croatia
Pfizer Investigational Site, Zagreb, , Croatia
Pfizer Investigational Site, Brno, , Czech Republic
Pfizer Investigational Site, Ceske Budejovice, , Czech Republic
Pfizer Investigational Site, Prague 2, , Czech Republic
Pfizer Investigational Site, Aarhus C, , Denmark
Pfizer Investigational Site, Esbjerg, , Denmark
Pfizer Investigational Site, Herlev, , Denmark
Pfizer Investigational Site, Herning, , Denmark
Pfizer Investigational Site, Hilleroed, , Denmark
Pfizer Investigational Site, Koebenhavn OE, , Denmark
Pfizer Investigational Site, Naestved, , Denmark
Pfizer Investigational Site, Roskilde, , Denmark
Pfizer Investigational Site, Vejle, , Denmark
Pfizer Investigational Site, Viborg, , Denmark
Pfizer Investigational Site, Cairo, , Egypt
Pfizer Investigational Site, Tartu, , Estonia
Pfizer Investigational Site, Angers, , France
Pfizer Investigational Site, Annecy Cedex, , France
Pfizer Investigational Site, Avignon Cedex 2, , France
Pfizer Investigational Site, Bordeaux, , France
Pfizer Investigational Site, Bordeaux, , France
Pfizer Investigational Site, Brest, , France
Pfizer Investigational Site, Caen Cedex 05, , France
Pfizer Investigational Site, Caen, , France
Pfizer Investigational Site, Clermont Ferrand, , France
Pfizer Investigational Site, Evreux, , France
Pfizer Investigational Site, Lagny Sur Marne, , France
Pfizer Investigational Site, Le Havre, , France
Pfizer Investigational Site, Le Mans, , France
Pfizer Investigational Site, Lille, , France
Pfizer Investigational Site, Lyon, , France
Pfizer Investigational Site, Marseille, , France
Pfizer Investigational Site, Meaux, , France
Pfizer Investigational Site, Montbeliard, , France
Pfizer Investigational Site, Mulhouse, , France
Pfizer Investigational Site, Nice, , France
Pfizer Investigational Site, Paris, , France
Pfizer Investigational Site, Paris, , France
Pfizer Investigational Site, Perpignan, , France
Pfizer Investigational Site, Rennes, , France
Pfizer Investigational Site, Rouen, , France
Pfizer Investigational Site, Saint-Herblain, , France
Pfizer Investigational Site, St Cloud, , France
Pfizer Investigational Site, Strasbourg, , France
Pfizer Investigational Site, Toulouse, , France
Pfizer Investigational Site, Berlin, , Germany
Pfizer Investigational Site, Berlin, , Germany
Pfizer Investigational Site, Chemnitz, , Germany
Pfizer Investigational Site, Erlangen, , Germany
Pfizer Investigational Site, Freiburg, , Germany
Pfizer Investigational Site, Gera, , Germany
Pfizer Investigational Site, Greiz, , Germany
Pfizer Investigational Site, Halle, , Germany
Pfizer Investigational Site, Halle, , Germany
Pfizer Investigational Site, Hamburg, , Germany
Pfizer Investigational Site, Hildburghausen, , Germany
Pfizer Investigational Site, Leipzig, , Germany
Pfizer Investigational Site, Luebeck, , Germany
Pfizer Investigational Site, Muenchen, , Germany
Pfizer Investigational Site, Riesa, , Germany
Pfizer Investigational Site, Rodewisch, , Germany
Pfizer Investigational Site, Saarbruecken, , Germany
Pfizer Investigational Site, Suhl, , Germany
Pfizer Investigational Site, Weiden, , Germany
Pfizer Investigational Site, Athens, Attiki, Greece
Pfizer Investigational Site, Athens, Attiki, Greece
Pfizer Investigational Site, Heraklion, Crete, Greece
Pfizer Investigational Site, New Territories, , Hong Kong
Pfizer Investigational Site, Budapest, , Hungary
Pfizer Investigational Site, Budapest, , Hungary
Pfizer Investigational Site, Budapest, , Hungary
Pfizer Investigational Site, Cork, Ireland, , Ireland
Pfizer Investigational Site, Cork, , Ireland
Pfizer Investigational Site, Dublin 9, , Ireland
Pfizer Investigational Site, Dublin, , Ireland
Pfizer Investigational Site, Galway, , Ireland
Pfizer Investigational Site, Haifa, , Israel
Pfizer Investigational Site, Haifa, , Israel
Pfizer Investigational Site, Jerusalem, , Israel
Pfizer Investigational Site, Jerusalem, , Israel
Pfizer Investigational Site, Kfar Saba, , Israel
Pfizer Investigational Site, Petah Tikva, , Israel
Pfizer Investigational Site, Rehovot, , Israel
Pfizer Investigational Site, Carpi, Modena, Italy
Pfizer Investigational Site, Alba (CN), , Italy
Pfizer Investigational Site, Aviano (PN), , Italy
Pfizer Investigational Site, Bergamo, , Italy
Pfizer Investigational Site, Biella, , Italy
Pfizer Investigational Site, Cagliari, , Italy
Pfizer Investigational Site, Casale Monferrato, AL, , Italy
Pfizer Investigational Site, Correggio, , Italy
Pfizer Investigational Site, Cremona, , Italy
Pfizer Investigational Site, Cuneo, , Italy
Pfizer Investigational Site, Fermo FM, , Italy
Pfizer Investigational Site, Firenze, , Italy
Pfizer Investigational Site, Genova, , Italy
Pfizer Investigational Site, Genova, , Italy
Pfizer Investigational Site, Lecco, , Italy
Pfizer Investigational Site, Lodi, , Italy
Pfizer Investigational Site, Mantova, , Italy
Pfizer Investigational Site, Milano, , Italy
Pfizer Investigational Site, Milano, , Italy
Pfizer Investigational Site, Milano, , Italy
Pfizer Investigational Site, Milano, , Italy
Pfizer Investigational Site, Modena, , Italy
Pfizer Investigational Site, Monserrato (CA), , Italy
Pfizer Investigational Site, Monza, , Italy
Pfizer Investigational Site, Napoli, , Italy
Pfizer Investigational Site, Palermo, , Italy
Pfizer Investigational Site, Parma, , Italy
Pfizer Investigational Site, Perugia, , Italy
Pfizer Investigational Site, Piacenza, , Italy
Pfizer Investigational Site, Pietra Ligure (SV), , Italy
Pfizer Investigational Site, Pisa, , Italy
Pfizer Investigational Site, Reggio Emilia, , Italy
Pfizer Investigational Site, Roma, , Italy
Pfizer Investigational Site, Sassari, , Italy
Pfizer Investigational Site, Terni, , Italy
Pfizer Investigational Site, Thiene (VI), , Italy
Pfizer Investigational Site, Torino, , Italy
Pfizer Investigational Site, Tortona, , Italy
Pfizer Investigational Site, Trescore Balneario BG, , Italy
Pfizer Investigational Site, Treviglio (BG), , Italy
Pfizer Investigational Site, Varese, , Italy
Pfizer Investigational Site, Luxembourg, , Luxembourg
Pfizer Investigational Site, Floriana, , Malta
Pfizer Investigational Site, Amersfoort, , Netherlands
Pfizer Investigational Site, Amsterdam, , Netherlands
Pfizer Investigational Site, Amsterdam, , Netherlands
Pfizer Investigational Site, Amsterdam, , Netherlands
Pfizer Investigational Site, Apeldoorn, , Netherlands
Pfizer Investigational Site, Blaricum, , Netherlands
Pfizer Investigational Site, Breda, , Netherlands
Pfizer Investigational Site, Delft, , Netherlands
Pfizer Investigational Site, Den Haag, , Netherlands
Pfizer Investigational Site, Eindhoven, , Netherlands
Pfizer Investigational Site, Enschede, , Netherlands
Pfizer Investigational Site, Groningen, , Netherlands
Pfizer Investigational Site, Groningen, , Netherlands
Pfizer Investigational Site, Hengelo, , Netherlands
Pfizer Investigational Site, Leeuwarden, , Netherlands
Pfizer Investigational Site, Leiden, , Netherlands
Pfizer Investigational Site, Leidschendam, , Netherlands
Pfizer Investigational Site, Podybus 90153, , Netherlands
Pfizer Investigational Site, Roermond, , Netherlands
Pfizer Investigational Site, Sittard, , Netherlands
Pfizer Investigational Site, Utrecht, , Netherlands
Pfizer Investigational Site, Veldhoven, , Netherlands
Pfizer Investigational Site, Zaandam, , Netherlands
Pfizer Investigational Site, Hamilton, Waikato, New Zealand
Pfizer Investigational Site, Auckland, , New Zealand
Pfizer Investigational Site, Bergen, , Norway
Pfizer Investigational Site, Bodo, , Norway
Pfizer Investigational Site, Fredrikstad, , Norway
Pfizer Investigational Site, Haugesund, , Norway
Pfizer Investigational Site, Levanger, , Norway
Pfizer Investigational Site, Mo i Rana, , Norway
Pfizer Investigational Site, Molde, , Norway
Pfizer Investigational Site, Notodden, , Norway
Pfizer Investigational Site, Oslo, , Norway
Pfizer Investigational Site, Rissa, , Norway
Pfizer Investigational Site, Rjukan, , Norway
Pfizer Investigational Site, Sandefjord, , Norway
Pfizer Investigational Site, Tonsberg, , Norway
Pfizer Investigational Site, Tromso, , Norway
Pfizer Investigational Site, Tromsø, , Norway
Pfizer Investigational Site, Lima, , Peru
Pfizer Investigational Site, Gdansk, , Poland
Pfizer Investigational Site, Gliwice, , Poland
Pfizer Investigational Site, Krakow, , Poland
Pfizer Investigational Site, Krakow, , Poland
Pfizer Investigational Site, Lodz, , Poland
Pfizer Investigational Site, Opole, , Poland
Pfizer Investigational Site, Poznan, , Poland
Pfizer Investigational Site, Sopot, , Poland
Pfizer Investigational Site, Warszawa, , Poland
Pfizer Investigational Site, Coimbra, , Portugal
Pfizer Investigational Site, Coimbra, , Portugal
Pfizer Investigational Site, Evora, , Portugal
Pfizer Investigational Site, Bucuresti, , Romania
Pfizer Investigational Site, Cluj Napoca, , Romania
Pfizer Investigational Site, Timisoara, , Romania
Pfizer Investigational Site, St. Petersburg, , Russian Federation
Pfizer Investigational Site, Belgrade, , Serbia
Pfizer Investigational Site, Sremska Kamenica, , Serbia
Pfizer Investigational Site, Banska Bystrica, , Slovakia
Pfizer Investigational Site, Bratislava, , Slovakia
Pfizer Investigational Site, Kosice, , Slovakia
Pfizer Investigational Site, Ljubljana, , Slovenia
Pfizer Investigational Site, Johannesburg, Gauteng, South Africa
Pfizer Investigational Site, Observatory, , South Africa
Pfizer Investigational Site, Alcoy, Alicante, Spain
Pfizer Investigational Site, Elche, Alicante, Spain
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Pfizer Investigational Site, Badalona, Barcelona, Spain
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Pfizer Investigational Site, San Sebastian, Guipuzcoa, Spain
Pfizer Investigational Site, Barbastro, Huesca, Spain
Pfizer Investigational Site, Reus, Tarragona, Spain
Pfizer Investigational Site, Albacete, , Spain
Pfizer Investigational Site, Alicante, , Spain
Pfizer Investigational Site, Badajoz, , Spain
Pfizer Investigational Site, Badajoz, , Spain
Pfizer Investigational Site, Cordoba, , Spain
Pfizer Investigational Site, Guadalajara, , Spain
Pfizer Investigational Site, Lleida, , Spain
Pfizer Investigational Site, Madrid, , Spain
Pfizer Investigational Site, Madrid, , Spain
Pfizer Investigational Site, Madrid, , Spain
Pfizer Investigational Site, Valencia, , Spain
Pfizer Investigational Site, Zaragoza, , Spain
Pfizer Investigational Site, Boras, , Sweden
Pfizer Investigational Site, Borås, , Sweden
Pfizer Investigational Site, Goteborg, , Sweden
Pfizer Investigational Site, Halmstad, , Sweden
Pfizer Investigational Site, Helsingborg, , Sweden
Pfizer Investigational Site, Kristianstad, , Sweden
Pfizer Investigational Site, Linkoping, , Sweden
Pfizer Investigational Site, Lund, , Sweden
Pfizer Investigational Site, Malmo, , Sweden
Pfizer Investigational Site, Motala, , Sweden
Pfizer Investigational Site, Norrkoping, , Sweden
Pfizer Investigational Site, Nässjö, , Sweden
Pfizer Investigational Site, Varnamo, , Sweden
Pfizer Investigational Site, Vasteras, , Sweden
Pfizer Investigational Site, Vastervik, , Sweden
Pfizer Investigational Site, Vaxjo, , Sweden
Pfizer Investigational Site, Basel, , Switzerland
Pfizer Investigational Site, Bellinzona, , Switzerland
Pfizer Investigational Site, Bern, , Switzerland
Pfizer Investigational Site, Bern, , Switzerland
Pfizer Investigational Site, Genève, , Switzerland
Pfizer Investigational Site, Huntingdon, Cambs, United Kingdom
Pfizer Investigational Site, Bournemouth, Dorset, United Kingdom
Pfizer Investigational Site, Hull, East Yorkshire, United Kingdom
Pfizer Investigational Site, Epping, Essex, United Kingdom
Pfizer Investigational Site, Westcliff-On-Sea, Essex, United Kingdom
Pfizer Investigational Site, Newport, Gwent, United Kingdom
Pfizer Investigational Site, Bangor, Gwynedd, United Kingdom
Pfizer Investigational Site, Salterhebble, Halifax, United Kingdom
Pfizer Investigational Site, Gosport, Hants, United Kingdom
Pfizer Investigational Site, Northwood, Middlesex, United Kingdom
Pfizer Investigational Site, Londonderry, N. Ireland, United Kingdom
Pfizer Investigational Site, Harrogate, N. Yorkshire, United Kingdom
Pfizer Investigational Site, Taunton, Somerset, United Kingdom
Pfizer Investigational Site, Swansea, South Wales, United Kingdom
Pfizer Investigational Site, York, Yorkshire, United Kingdom
Pfizer Investigational Site, Belfast, , United Kingdom
Pfizer Investigational Site, Bradford, , United Kingdom
Pfizer Investigational Site, Bristol, , United Kingdom
Pfizer Investigational Site, Cardiff, , United Kingdom
Pfizer Investigational Site, Coventry, , United Kingdom
Pfizer Investigational Site, East Kilbride, , United Kingdom
Pfizer Investigational Site, Huddersfield, , United Kingdom
Pfizer Investigational Site, Leeds, , United Kingdom
Pfizer Investigational Site, Leeds, , United Kingdom
Pfizer Investigational Site, Lincoln, , United Kingdom
Pfizer Investigational Site, London, , United Kingdom
Pfizer Investigational Site, London, , United Kingdom
Pfizer Investigational Site, London, , United Kingdom
Pfizer Investigational Site, London, , United Kingdom
Pfizer Investigational Site, London, , United Kingdom
Pfizer Investigational Site, Luton, , United Kingdom
Pfizer Investigational Site, Manchester, , United Kingdom
Pfizer Investigational Site, Sheffield, , United Kingdom
Pfizer Investigational Site, Shrewsbury, , United Kingdom
Pfizer Investigational Site, Somerset, , United Kingdom
Pfizer Investigational Site, Southampton, , United Kingdom
Pfizer Investigational Site, Steeton, , United Kingdom
Pfizer Investigational Site, Stoke on Trent, , United Kingdom
Pfizer Investigational Site, Telford, , United Kingdom
Pfizer Investigational Site, Wythenshawe, Manchester, , United Kingdom
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR