The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Brief Title: Bone Loss Treatment From Adjuvant Zoledronate Efficacy
Official Title: An Open,Multicentre,Prospective Study of Adjuvant Zoledronate Treatment in Osteoporosis Women With Breast Cancer
Study ID: NCT01623908
Brief Summary: The main purpose of this study is to observe and assess the impact of adjuvant zoledronate on bone density in breast cancer patients. The second purposes: * The efficacy of adjuvant zoledronate * The safety of adjuvant zoledronate * The bone loss of breast cancer patients in Guangdong * The correlation between bone loss of breast cancer patients and treatment of disease in Guangdong
Detailed Description: Breast cancer is the most commonly diagnosed malignant disease and the leading cause of cancer-related mortality among women. Zoledronate is a bone-targeted bisphosphonate, which is used to treat osteoporosis and to reduce the risk of skeletal morbidity in patients with bone metastases. Zoledronate can also reduce the persistence of disseminated tumour cells in the bone marrow of women with early-stage breast cancer. Nowadays, consensus is emerging that certain subsets of patients with early-stage breast cancer may benefit from bisphosphonate therapy.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Dongguan People's Hospital, Dongguan, Guangdong, China
General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guangdong, China
Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China
Guangdong General Hospital, Guangzhou, Guangdong, China
GuangDong Hospital Of Traditional Chinese Medicine, Guangzhou, Guangdong, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China
Guangzhou First Municipal People's Hospital, Guangzhou, Guangdong, China
Nanfang Hospital, Guangzhou, Guangdong, China
The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China
Shenzhen Second Municipal People's Hospital, Shenzhen, Guangdong, China
Name: Shenming Wang, MD, PhD
Affiliation: First Affiliated Hospital, Sun Yat-Sen University
Role: STUDY_CHAIR
Name: Ying Lin, MD, PhD
Affiliation: First Affiliated Hospital, Sun Yat-Sen University
Role: PRINCIPAL_INVESTIGATOR