Spots Global Cancer Trial Database for External Hypofractionated Radiotherapy With Simultaneous Integrated Boost in Early Breast Cancer Patients

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Trial Identification

Brief Title: External Hypofractionated Radiotherapy With Simultaneous Integrated Boost in Early Breast Cancer Patients

Official Title: A Prospective Phase II Trial of an Accelerated Hypofractionated Radiotherapy Schedule With Risk-adapted Simultaneous Integrated Boost (HF-SIB) in Early Breast Cancer Patients Undergoing Breast Conserving Surgery

Study ID: NCT06224244

Conditions

Breast Neoplasms

Breast Cancer

Interventions

Ten-fraction hypofractionated breast radiotherapy with 40 Gy simultaneous integrated bed boost

Ten-fraction hypofractionated breast radiotherapy with 43 Gy simultaneous integrated bed boost

Study Description

Brief Summary: This is a prospective non randomized phase two trial evaluating the feasibility of a ten fraction accelerated hypofractionated radiotherapy schedule with simultaneous integrated boost risk adapted in patients undergoing breast conserving surgery for early breast cancer

Detailed Description: Patients enrolled for the study, according to eligibility criteria, undergo breast conserving surgery followed by adjuvant 10-fraction whole breast irradiation with a risk adapted simultaneous-integrated boost dose at the level of the tumour bed according to clinical and pathological risk factors.