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Brief Title: A Study Of SU011248 Plus Paclitaxel Versus Bevacizumab Plus Paclitaxel In Patients With Advanced Breast Cancer
Official Title: A Phase 3 Study Of SU011248 In Combination With Paclitaxel Versus Bevacizumab With Paclitaxel In The First-Line Advanced Disease Setting In Patients Having Breast Cancer
Study ID: NCT00373256
Brief Summary: To compare treatment with SU011248 plus paclitaxel versus bevacizumab plus paclitaxel to determine which treatment works better against breast cancer
Detailed Description: On May 27, 2009, the independent Data Monitoring Committee (DMC) reviewed the progress of Study A6181094. The DMC determined Study A6181094 had met pre-specified futility criteria and was unlikely to meet its primary endpoint to demonstrate a statistically significant improvement in progression-free survival (PFS) in patients treated with sunitinib plus paclitaxel versus bevacizumab plus paclitaxel. Pfizer notified clinical trial investigators involved in the study and regulatory agencies of these findings. Enrollment in this study has been stopped.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Pfizer Investigational Site, Bessemer, Alabama, United States
Pfizer Investigational Site, Birmingham, Alabama, United States
Pfizer Investigational Site, Birmingham, Alabama, United States
Pfizer Investigational Site, Birmingham, Alabama, United States
Pfizer Investigational Site, Birmingham, Alabama, United States
Pfizer Investigational Site, Birmingham, Alabama, United States
Pfizer Investigational Site, Daphne, Alabama, United States
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Pfizer Investigational Site, Flagstaff, Arizona, United States
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Pfizer Investigational Site, Hot Springs, Arkansas, United States
Pfizer Investigational Site, Anaheim, California, United States
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Pfizer Investigational Site, Baldwin Park, California, United States
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Pfizer Investigational Site, Irvine, California, United States
Pfizer Investigational Site, La Jolla, California, United States
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Pfizer Investigational Site, Los Angeles, California, United States
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Pfizer Investigational Site, Martinez, California, United States
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Pfizer Investigational Site, Mountain View, California, United States
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Pfizer Investigational Site, Riverside, California, United States
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Pfizer Investigational Site, San Diego, California, United States
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Pfizer Investigational Site, San Francisco, California, United States
Pfizer Investigational Site, San Francisco, California, United States
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Pfizer Investigational Site, Aurora, Colorado, United States
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Pfizer Investigational Site, Denver, Colorado, United States
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Pfizer Investigational Site, Louisville, Kentucky, United States
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Pfizer Investigational Site, Annapolis, Maryland, United States
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Pfizer Investigational Site, Columbia, Maryland, United States
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Pfizer Investigational Site, Burlington, Massachusetts, United States
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Pfizer Investigational Site, Coon Rapids, Minnesota, United States
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Pfizer Investigational Site, Las Vegas, Nevada, United States
Pfizer Investigational Site, Las Vegas, Nevada, United States
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Pfizer Investigational Site, Round Rock, Texas, United States
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Pfizer Investigational Site, San Antonio, Texas, United States
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Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR