⭐️⭐️⭐️⭐️⭐️ "A total no brainer"

⭐️⭐️⭐️⭐️⭐️ "Love this, so easy."

Spots is the easy way to track your skin, mole and cancer changes.

Spots Global Cancer Trial Database for A Study of E7389 in Advanced/Metastatic Breast Cancer Patients

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: A Study of E7389 in Advanced/Metastatic Breast Cancer Patients

Official Title: A Phase II Open Label Study of E7389 (Halichondrin B Analog) in Patients With Advanced/Metastatic Breast Cancer Previously Treated With Chemotherapy Including An Anthracycline and A Taxane

Study ID: NCT00097721

Interventions

E7389

Study Description

Brief Summary: The purpose of this study is to determine if E7389 is a safe and effective treatment for advanced/metastatic breast cancer.

Detailed Description: The primary objective is to determine the response rate (RR) to E7389 monotherapy administered as an IV bolus of 1.4 mg/m\^2 on Days 1, 8, and 15 of a 28-Day cycle and on Days 1 and 8 of a 21-day cycle in patients with advanced/metastatic breast cancer treated with chemotherapy including an anthracycline and a taxane, with previously documented progression during or within six months following the last dose of prior chemotherapy. The secondary objectives are to evaluate: * The safety and tolerability of E7389 monotherapy in this patient population; * The antitumor activity of E7389 as determined by duration of response, time to progression, and overall survival; * Quality of life measured by the Functional Assessment of Cancer Therapy-Breast (FACT-B) questionnaire/tumor-related symptom improvement or worsening measured by pain intensity on a visual analog scale (VAS), analgesics consumption, weight changes and performance status (PS); * Tumor pharmacogenetics and their possible relationship to response (assessment of beta-tubulin isotype mRNA on biopsy sample) in patients who have signed a separate consent form

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

, Jonesboro, Arkansas, United States

, Deer Park, California, United States

, La Verne, California, United States

, Pasadena, California, United States

, Pomona, California, United States

, Brooksville, Florida, United States

, New Port Richey, Florida, United States

, Plantation, Florida, United States

, New Orleans, Louisiana, United States

, Southaven, Mississippi, United States

, Missoula, Montana, United States

, Syracuse, New York, United States

, Middletown, Ohio, United States

, Memphis, Tennessee, United States

, Amarillo, Texas, United States

, Richardson, Texas, United States

Contact Details

Name: Dale Shuster, Ph.D.

Affiliation: Eisai Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

Logo

Take Control of Your Skin and Body Changes Today.

Try out Spots for free, set up only takes 2 mins.

spots app storespots app store

Join others from around the world: