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Spots Global Cancer Trial Database for Vinflunine Plus Trastuzumab in Human Epidermal Growth Factor Receptor 2 (HER2neu) Over-Expressing Metastatic Breast Cancer

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Trial Identification

Brief Title: Vinflunine Plus Trastuzumab in Human Epidermal Growth Factor Receptor 2 (HER2neu) Over-Expressing Metastatic Breast Cancer

Official Title: Phase II Trial of Vinflunine Plus Trastuzumab in Human Epidermal Growth Factor Receptor 2 (HER2neu) Over-Expressing Metastatic Breast Cancer

Study ID: NCT00284180

Study Description

Brief Summary: This research study involves the anti-cancer medication trastuzumab and the investigational drug vinflunine. The purpose of this trials is to see if trastuzumab and vinflunine used in combination or vinflunine alone is effective in the treatment of metastatic breast cancer

Detailed Description: If the tumor is HER2neu positive, eligible patients will receive trastuzumab and vinflunine intravenously (IV) every 3 weeks. If the tumor is HER2neu negative, eligible patients will receive vinflunine intravenously (IV) every 3 weeks. Patients whose cancer does not grow or decreases in size may continue to receive treatment until cancer progression. Evaluation of cancer will be every 9 weeks.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Northeast Alabama Regional Medical Center, Anniston, Alabama, United States

Florida Cancer Specialists, Fort Myers, Florida, United States

Integrated Community Oncology Network, Jacksonville, Florida, United States

Watson Clinic Center for Cancer Care and Research, Lakeland, Florida, United States

Northeast Georgia Medical Center, Gainesville, Georgia, United States

Hematology Oncology Life Center, Alexandria, Louisiana, United States

Grand Rapids Clinical Oncology Program, Grand Rapids, Michigan, United States

Spartanburg Regional Medical Center, Spartanburg, South Carolina, United States

Associates in Hematology Oncology, Chattanooga, Tennessee, United States

Tennessee Oncology, Nashville, Tennessee, United States

Contact Details

Name: Denise A Yardley, MD

Affiliation: SCRI Development Innovations, LLC

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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