Spots Global Cancer Trial Database for A Study of Nivolumab and Ipilimumab and Nivolumab Alone in Combination With Trans-arterial ChemoEmbolization (TACE) in Participants With Intermediate Stage Liver Cancer
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Trial Identification
Brief Title: A Study of Nivolumab and Ipilimumab and Nivolumab Alone in Combination With Trans-arterial ChemoEmbolization (TACE) in Participants With Intermediate Stage Liver Cancer
Official Title: A Randomized, Multi-center, Double-blinded, Placebo-controlled Phase 3 Study of Nivolumab and Ipilimumab, Nivolumab Monotherapy, or Placebo in Combination With Trans-arterial ChemoEmbolization (TACE) in Patients With Intermediate-stage Hepatocellular Carcinoma (HCC)
Study ID: NCT04340193
Conditions
Study Description
Brief Summary: The purpose of this study is to evaluate the safety and tolerability of nivolumab with and without ipilimumab in combination with Trans-arterial ChemoEmbolization (TACE) to TACE alone in participants with intermediate liver cancer.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Local Institution - 0189, Coronado, California, United States
Local Institution, Washington, District of Columbia, United States
Local Institution - 0005, Louisville, Kentucky, United States
Norton Cancer Institute Audubon, Louisville, Kentucky, United States
Local Institution - 0109, Dallas, Texas, United States
Local Institution, Wollongong, New South Wales, Australia
Local Institution - 0037, Birtinya, Queensland, Australia
Local Institution - 0010, Adelaide, South Australia, Australia
Local Institution - 0001, Melbourne, Victoria, Australia
Local Institution - 0139, Murdoch, Western Australia, Australia
Local Institution - 0048, Wiener Neustadt, Niederosterreich, Austria
Local Institution - 0026, Graz, , Austria
Local Institution - 0013, St. Polten, , Austria
Local Institution, Vienna, , Austria
Local Institution - 0078, West Springfield, , Austria
Local Institution - 0020, Brussels, , Belgium
Local Institution, Federal District, , Belgium
Local Institution - 0053, Gent, , Belgium
Local Institution - 0050, Plainfield, , Belgium
Local Institution - 0039, Quebec, , Canada
Local Institution - 0184, Beijing, Beijing, China
Local Institution, Guangzhou, Guangdong, China
Local Institution, Guangzhou, Guangdong, China
Local Institution, Tianjin, Hebei, China
Local Institution - 0196, Nanjing, Jiangsu, China
Local Institution - 0176, Nanchang, Jiangxi, China
Local Institution, Shenyang, Liaoning, China
Local Institution - 0209, Xi'an, Shan3xi, China
Local Institution - 0151, Shanghai, Shanghai, China
Local Institution, Chengdu, Sichuan, China
Local Institution, Hangzhou, Zhejiang, China
Local Institution, Hangzhou, Zhejiang, China
Local Institution - 0055, Olomouc, , Czechia
Local Institution, Praha 5, , Czechia
Local Institution - 0014, Lille, Mount, France
Local Institution - 0132, Caen, , France
Local Institution - 0021, Clichy, , France
Local Institution - 0064, Dijon, , France
Local Institution - 0082, Englewood, , France
Local Institution - 0052, La Tronche, , France
Local Institution - 0061, Marseil, , France
Local Institution - 0087, Nantes, , France
Local Institution - 0012, Nice, , France
Local Institution - 0093, Paris, , France
Local Institution - 0046, Reims, , France
Local Institution - 0094, Villejuif cedex, , France
Local Institution - 0035, Goettingen, , Germany
Local Institution, Hannover, , Germany
Local Institution, Heidelberg, , Germany
Local Institution - 0071, Leipzig, , Germany
Local Institution - 0045, Hong Kong, , Hong Kong
Local Institution - 0004, HongKong, , Hong Kong
Local Institution - 0015, Orbassano, TO, Italy
Local Institution, Messina, , Italy
Local Institution - 0025, Milano, , Italy
Local Institution, Monserrato, , Italy
Local Institution, Parma, , Italy
Local Institution, Roma, , Italy
Local Institution - 0076, Siena, , Italy
Local Institution - 0070, Vicenza, , Italy
Local Institution - 0122, Matsuyama, Ehime, Japan
Local Institution - 0148, Sapporo-shi, Hokkaido, Japan
Local Institution - 0118, Kanazawa, Ishikawa, Japan
Local Institution - 0116, Kawasaki, Kanagawa, Japan
Local Institution - 0120, Yokohama-shi, Kanagawa, Japan
Local Institution - 0113, Yokohama-Shi, Kanagawa, Japan
Local Institution - 0115, Kyoto-Shi, Kyoto, Japan
Local Institution - 0127, Abeno-ku, Osaka, Japan
Local Institution - 0125, Izunokuni-Shi, Shizuoka, Japan
Local Institution - 0128, Minato-ku, Tokyo, Japan
Local Institution - 0121, Musashino-shi, Tokyo, Japan
Local Institution - 0108, Chiba, , Japan
Local Institution - 0119, Hiroshima, , Japan
Local Institution - 0117, Osaka, , Japan
Local Institution - 0123, Saitama, , Japan
Local Institution - 0114, Busan, , Korea, Republic of
Local Institution - 0135, Daegu, , Korea, Republic of
Local Institution - 0047, Gyeongsangnam-do, , Korea, Republic of
Local Institution - 0097, Hwasun-Gun, , Korea, Republic of
Local Institution - 0161, Seoul, , Korea, Republic of
Local Institution - 0186, Seoul, , Korea, Republic of
Local Institution - 0160, Seoul, , Korea, Republic of
Local Institution - 0164, Seoul, , Korea, Republic of
Local Institution, Warszawa, , Poland
Local Institution - 0049, San Juan, , Puerto Rico
Local Institution - 0016, Barnaul, , Russian Federation
Local Institution - 0077, Saint Petersburg, , Russian Federation
Local Institution - 0009, Saint-Petersburg, , Russian Federation
Local Institution, Singapore, , Singapore
Local Institution - 0089, Singapore, , Singapore
Local Institution - 0011, Singapore, , Singapore
Local Institution - 0023, Alicante, , Spain
Local Institution - 0092, Cordoba, , Spain
Local Institution - 0101, Madrid, , Spain
Local Institution - 0183, Madrid, , Spain
Local Institution - 0084, Madrid, , Spain
Local Institution - 0018, Madrid, , Spain
Local Institution - 0099, Pamplona, , Spain
Local Institution - 0131, Sabadell, , Spain
Local Institution - 0102, Santiago de Compostela, , Spain
Local Institution - 0141, Kaohsiung, , Taiwan
Local Institution - 0136, Puzi City, , Taiwan
Local Institution - 0030, Taichung City, , Taiwan
Local Institution - 0057, Taichung, , Taiwan
Local Institution - 0029, Tainan City, , Taiwan
Local Institution - 0002, Taipei, , Taiwan
Local Institution - 0044, Tapei, , Taiwan
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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