Spots Global Cancer Trial Database for Optimization of MRI for Radiation Therapy
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Trial Identification
Brief Title: Optimization of MRI for Radiation Therapy
Official Title: Optimization of MRI for Radiation Therapy
Study ID: NCT02045381
Interventions
Study Description
Brief Summary: Currently, appropriate patients undergo MRI imaging with immobilization and sequences optimized for diagnostic radiology purposes. Using a mutual information algorithm, these images are then registered to a treatment planning CT obtained with custom immobilization to minimize intra-and inter-treatment motion and positional variation. This image registration process is time-consuming and introduces additional layers of geometric uncertainty into what should be a highly precise treatment planning process. However, it is necessary, since radiation dose calculations cannot be performed on MRI data due to the lack of crucial density information. The investigator envisions CT-less treatment planning, using only MRI, due to superior imaging characteristics, fully integrated into the radiation oncology clinic. This study will begin this process.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Univeristy of Michigan, Ann Arbor, Michigan, United States
Contact Details
Name: Shruti Jolly, MD
Affiliation: University of Michigan
Role: PRINCIPAL_INVESTIGATOR
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