Spots Global Cancer Trial Database for Timing of Resective Surgery After Neoadjuvant Chemoradiotherapy in Esophageal Cancer
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Trial Identification
Brief Title: Timing of Resective Surgery After Neoadjuvant Chemoradiotherapy in Esophageal Cancer
Official Title: Randomized Clinical Trial Comparing the Timing of Resective Surgery After Neoadjuvant Chemoradiotherapy in Cancer of the Esophagus or Gastric Cardia
Study ID: NCT02415101
Conditions
Interventions
Study Description
Brief Summary: This study compares outcomes with regard to the timing of resective surgery after neoadjuvant chemoradiotherapy (CRT) in cancer of the esophagus or gastric cardia. Patients are randomised to surgery either conventional 4-6 or 10-12 weeks after termination of CRT. The study hypothesis is that a longer delay improves histological response and decreases the risk of postoperative morbidity and mortality.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Surgery Gastrocentrum Karolinska Univeristy Hospital, Stockholm, , Sweden
Contact Details
Name: Magnus Nilsson, Prof
Affiliation: Karolinska University Hospital
Role: PRINCIPAL_INVESTIGATOR
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