Spots Global Cancer Trial Database for Role of microRNA in the Development of Cutaneous Squamous Cell Carcinoma
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Trial Identification
Brief Title: Role of microRNA in the Development of Cutaneous Squamous Cell Carcinoma
Official Title:
Study ID: NCT01143311
Conditions
Interventions
Study Description
Brief Summary: The aim of this study is to analyze the differential expression of the miR transcriptome in the distinctive stages of the development of cutaneous squamous cell carcinoma (C-SCC). In this aim the investigators plan to recruit a cohort of 20 patients suffering of C-SCC and to collect from each of them, biopsies corresponding to i) non UV-exposed areas ii) UV-exposed areas, iii) actinic keratosis and iv) tumoral regions. Total RNAs will be prepared from each biopsy and the miRNA profiles will be characterized using a dedicated miR array.
Detailed Description:
Keywords
Eligibility
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
CHU de Nice - 4 avenue Reine Victoria - Hôpital de Cimiez, Nice, Alpes-Maritimes, France
Contact Details
Name: Thierry Passeron, PhD
Affiliation: CHU de Nice - Service de Dermatologie - Hôpital de l'Archet - 151 Route de saint-antoine de ginestière 06200 Nice
Role: PRINCIPAL_INVESTIGATOR
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