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Brief Title: A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab
Official Title: Phase 2 Study Comparing Efficacy and Safety of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab
Study ID: NCT03368859
Brief Summary: A study to evaluate the efficacy and tolerability of ABT-165 plus FOLFIRI compared to bevacizumab plus FOLFIRI in participants with previously treated metastatic adenocarcinoma of the colon or rectum.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Ironwood Cancer & Res Ctr /ID# 200044, Chandler, Arizona, United States
Highlands Oncology Group /ID# 169289, Fayetteville, Arkansas, United States
City of Hope /ID# 200501, Duarte, California, United States
St. Joseph Heritage Healthcare /ID# 200100, Fullerton, California, United States
USC Norris Cancer Center /ID# 200410, Los Angeles, California, United States
Hoag Memorial Hosp Presbyterian /ID# 202661, Newport Beach, California, United States
Torrance Health Association (DBA)Torrance Memorial Physician Network/Cancer Care /ID# 202488, Redondo Beach, California, United States
UC Davis Comprehensive Cancer Center - Main /ID# 207227, Sacramento, California, United States
Pacific Central Coast Health Centers-SLO Oncology and Hematology Health Center /ID# 201215, San Luis Obispo, California, United States
Central Coast Medical Oncology /ID# 200227, Santa Maria, California, United States
University of California, Los /ID# 169294, Santa Monica, California, United States
Kaiser Permanente, Waterpark III Institute for Health Research /ID# 200801, Aurora, Colorado, United States
Georgetown University Hospital /ID# 202903, Washington, District of Columbia, United States
Florida Cancer Specialist - South /ID# 203796, Fort Myers, Florida, United States
Florida Cancer Specialists-Panhandle /ID# 203787, Tallahassee, Florida, United States
IACT Health /ID# 169292, Columbus, Georgia, United States
Ingalls Memorial Hosp /ID# 169892, Harvey, Illinois, United States
Illinois Cancer Care, PC /ID# 202189, Peoria, Illinois, United States
Fort Wayne Medical Oncology /ID# 201616, Fort Wayne, Indiana, United States
Cancer Center of Kansas /ID# 200627, Wichita, Kansas, United States
Norton Cancer Institute /ID# 200674, Louisville, Kentucky, United States
Ochsner Clinic Foundation-New Orleans /ID# 169291, New Orleans, Louisiana, United States
Whiteside Institute for Clinic /ID# 200802, Duluth, Minnesota, United States
Mmcorc /Id# 202099, Saint Louis Park, Minnesota, United States
Washington University School /ID# 200621, Saint Louis, Missouri, United States
University of Nebraska /ID# 203195, Omaha, Nebraska, United States
The Valley Hospital /ID# 169999, Paramus, New Jersey, United States
Duke University Medical Center /ID# 169657, Durham, North Carolina, United States
Fairview Hospital - Moll Pavilion /ID# 205910, Cleveland, Ohio, United States
Cleveland Clinic Main Campus /ID# 200325, Cleveland, Ohio, United States
Hillcrest Hospital /ID# 205911, Mayfield Heights, Ohio, United States
INTEGRIS Cancer Institute of OK/INTEGRIS Southwest Medical Center /ID# 200831, Oklahoma City, Oklahoma, United States
INTEGRIS Cancer Institute /ID# 200832, Oklahoma City, Oklahoma, United States
Oregon Health and Science University /ID# 170807, Portland, Oregon, United States
Thomas Jefferson University /ID# 200833, Philadelphia, Pennsylvania, United States
UPMC Hillman Cancer Ctr /ID# 200672, Pittsburgh, Pennsylvania, United States
Greenville Hospital System /ID# 203021, Greenville, South Carolina, United States
Tennessee Oncology-Nashville Centennial /ID# 203424, Nashville, Tennessee, United States
Tennessee Oncology, PLLC /ID# 203581, Nashville, Tennessee, United States
Ut Southwestern Medical Center /Parkland Health and Hospital System /Id# 210112, Dallas, Texas, United States
UTSW-Dallas /ID# 204031, Dallas, Texas, United States
Millennium Oncology /ID# 204925, Houston, Texas, United States
Virginia Cancer Specialists /ID# 169293, Fairfax, Virginia, United States
Kadlec Clinic Hematology and O /ID# 170811, Kennewick, Washington, United States
Medical Oncology Associates /ID# 169290, Spokane, Washington, United States
Univ of Wisconsin Hosp/Clinics /ID# 200424, Madison, Wisconsin, United States
UZ Gent /ID# 200691, Gent, Oost-Vlaanderen, Belgium
Imelda Ziekenhuis /ID# 200693, Bonheiden, , Belgium
Cliniques universitaires Saint /ID# 203101, Brussels, , Belgium
UZ Antwerp /ID# 200694, Edegem, , Belgium
UZ Leuven /ID# 200001, Leuven, , Belgium
Hospital Maisonneuve-Rosemont /ID# 171590, Montreal, Quebec, Canada
Jewish General Hospital /ID# 171584, Montreal, Quebec, Canada
National Cancer Center /ID# 170879, Goyang, Gyeonggido, Korea, Republic of
Samsung Medical Center /ID# 170875, Seoul, Seoul Teugbyeolsi, Korea, Republic of
Seoul National University Hospital /ID# 170878, Seoul, , Korea, Republic of
Asan Medical Center /ID# 170877, Seoul, , Korea, Republic of
Hospital Universitario Vall d'Hebron /ID# 200186, Barcelona, , Spain
Hospital General Universitario Gregorio Maranon /ID# 200189, Madrid, , Spain
Hospital Clinico Universitario San Carlos /ID# 201721, Madrid, , Spain
Hospital Universitario Fundacion Jimenez Diaz /ID# 200187, Madrid, , Spain
Hospital Universitario HM Sanchinarro /ID# 200190, Madrid, , Spain
National Taiwan Univ Hosp /ID# 170677, Taipei City, Taipei, Taiwan
Taichung Veterans General Hosp /ID# 170123, Taichung City, , Taiwan
Taipei Veterans General Hosp /ID# 170675, Taipei City, , Taiwan
Name: AbbVie Inc.
Affiliation: AbbVie
Role: STUDY_DIRECTOR