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Spots Global Cancer Trial Database for Corticosteroids for Cancer Pain

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Corticosteroids for Cancer Pain

Official Title: Corticosteroids for Cancer Pain

Study ID: NCT00676936

Conditions

Cancer
Pain

Study Description

Brief Summary: Study hypothesis: corticosteroids are effective for pain in cancer patients. We will perform a double-blind, randomized, placebo-controlled multicentre trial evaluating the effect of Methylprednisolone 16 mg twice daily in cancer patients with pain (average pain last 24 hrs NRS \> 4 (Numerical rating scale, 0 No pain, 10 worst pain).

Detailed Description: Patients are required to use strong opioids before entering the study. Weak opioids are allowed if patients have short acting strong opioids as rescue-medication. The scheduled opioids shall be stable last 48 hours before entering the study and will be kept stable during the study period. Patients may use as much short acting rescue-medication as they require. No other analgesic medication should be started during the study period. The study is a multicentre trial. Patients will be randomized according to 1. study centre (No 1-5) and 2. pain mechanism: skeletal metastases (yes/no). Patients are evaluated Day 0 and Day 7 by palliative care physician. Patients will be contacted by phone Day 1-6 and will fill in questionnaire regarding symptoms and analgesic usage. Patients will be contacted Day 14 and 21 to fill in questionnaires regarding symptoms, quality of life and side effects.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Haraldsplass Diakonale sykehus, Bergen, , Norway

Sykehuset Buskerud HF, Drammen, , Norway

Sørlandet Sykehus HF, Kristiansand, , Norway

Oslo Universitetssykehus, Ulleval, Oslo, , Norway

Sykehuset Telemark HF, Skien, , Norway

St Olavs Hospital HF, Trondheim, , Norway

Contact Details

Name: Stein Kaasa, MD PhD prof

Affiliation: Norwegian University of Science and Technology

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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