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Spots Global Cancer Trial Database for Safety Study of MPC-3100 in Cancer Patients Who Have Failed Other Treatments

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Safety Study of MPC-3100 in Cancer Patients Who Have Failed Other Treatments

Official Title: Phase 1 Study of MCP-3100 in Patients With Refractory or Relapsed Cancer

Study ID: NCT00920205

Conditions

Cancer

Study Description

Brief Summary: The purpose of this study is to see how safe the study drug is and to determine the best dose to use in cancer patients in the future. The study drug is designed to reduce the activity of a protein known as "heat shock protein 90", or "Hsp90". Hsp90 is found in every cell in the human body and normally helps those cells (and the body) cope with stressful situations. In certain cancers, however, Hsp90 helps the cancer cells survive and grow. By reducing the activity of Hsp90, the study drug may slow the growth, and reduce the survival, of those cancer cells.

Detailed Description: This is a dose escalation study. As subjects participating in the study tolerate a specific dose level, the new subjects entering will be given a higher dose of the study drug.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Nevada Cancer Institute, Las Vegas, Nevada, United States

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

South Texas Accelerated Research Therapeutics, San Antonio, Texas, United States

Contact Details

Name: Andrew Beelen, MD

Affiliation: Myrexis Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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