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Brief Title: Cohort Study to Identify Cancer Patients at High Risk of Venous Thromboembolism
Official Title: Microparticle's Procoagulant Activity to Identify Patients With Cancer and a High Risk for Venous Thrombosis
Study ID: NCT02095925
Brief Summary: Cancer patients are at increased risk of deep venous thrombosis and pulmonary embolism, collectively termed venous thromboembolism (VTE). Risk assessment scores for VTE in cancer patients have been previously developed by the groups of Khorana and Vienna CATS. However, routine thromboprophylaxis for ambulatory cancer patients based on these scores is currently not recommended. In the investigators prospective, observational cohort study, the investigators aim to identify cancer patients at high risk for VTE based on clinical characteristics, coagulation biomarkers and the coagulant activity of tissue factor bearing microparticles.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Hopital Louis Mourier, Colombes, Ile-de-France, France
Hospital D'Annunziata, Chieti, , Italy
Instituto Nacional de Cancerología, Mexico City, , Mexico
Slotervaart hospital, Amsterdam, Noord-Holland, Netherlands
VU medical center, Amsterdam, Noord-Holland, Netherlands
Academic Medical Center, Amsterdam, Noord-Holland, Netherlands
University Medical Center Groningen, Groningen, , Netherlands
Name: Harry R Buller, MD PhD
Affiliation: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Role: PRINCIPAL_INVESTIGATOR