Spots Global Cancer Trial Database for The FuSion Program: A Prospective and Multicenter Cohort Study of Pan-Cancer Screening in Chinese Population
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Trial Identification
Brief Title: The FuSion Program: A Prospective and Multicenter Cohort Study of Pan-Cancer Screening in Chinese Population
Official Title: A Prospective, Multicenter, Noninterventional Cohort Study of Muti-Omics Models for Pan-Cancer Screening
Study ID: NCT05159544
Conditions
Interventions
Study Description
Brief Summary: The integrative study by Fudan and Singlera for cancer early detection(The FuSion Program ) will evaluate sensitivity,specificity and positive/negative predictive value of the screening model jointly developed by FuDan University and Singlera in a 2-year follow-up corhort including 10,000 persons in routine annual physicals from dozens of hospitals. The multi-omics model for pan-cancer screening will be developed in a 3-year follow-up corhort including 50,000 natural persons in community containing genetic information of tumor families, assessment of epidemiological risk factors, tumor markers, proteomics, genomics and DNA methylation. After optimizing, the ability of this model will be validated in the Taizhou corhort in reality.
Detailed Description:
Eligibility
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
The First Affiliated Hospital of USTC (Anhui Provincial Hospital), Hefei, Anhui, China
Beijing Hospital, Beijing, Beijing, China
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China
Union Hospital affiliated to Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China
Third Xiangya Hospital of Central South University, Changsha, Hunan, China
Xiangya Hospital of Central South University, Changsha, Hunan, China
Jiangsu Province Hospital, Nanjing, Jiangsu, China
Fudan University Taizhou Institute of Health Sciences, Taizhou, China, Taihou, Jiangsu, China
Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
Sichuan Provincial People's Hospital, Chengdu, Sichuan, China
West China Hospital of Sichuan University, Chengdu, Sichuan, China
Contact Details
Name: Xingdong Chen, Ph.D
Affiliation: Fudan University Taizhou Institute of Health Sciences, Taizhou, China
Role: STUDY_DIRECTOR
Name: Rui Liu, Ph.D
Affiliation: Singlera Genomics Inc.
Role: PRINCIPAL_INVESTIGATOR
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