Spots Global Cancer Trial Database for SC-004 Alone or With ABBV-181 in Subjects With Epithelial Ovarian, Fallopian Tube, Primary Peritoneal and Endometrial Cancers
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Trial Identification
Brief Title: SC-004 Alone or With ABBV-181 in Subjects With Epithelial Ovarian, Fallopian Tube, Primary Peritoneal and Endometrial Cancers
Official Title: An Open Label, Phase 1 Study of SC-004 as Monotherapy and in Combination With ABBV-181 in Subjects With Epithelial Ovarian, Including Fallopian Tube and Primary Peritoneal and Endometrial Cancers
Study ID: NCT03138408
Conditions
Study Description
Brief Summary: This is a two-part study consisting of Part A (dose regimen finding) followed by Part B (dose expansion). Part A (dose regimen finding) will allow definition of the maximum tolerated dose (MTD) through dose escalation and possible dose interval modification. In Part B (dose expansion), potential therapeutic doses may be studied with SC-004 as monotherapy and SC-004 in combination with ABBV-181 in disease-specific cohorts.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
University of Alabama /ID# 202249, Birmingham, Alabama, United States
Highlands Oncology Group /ID# 209165, Fayetteville, Arkansas, United States
City of Hope /ID# 202493, Duarte, California, United States
University of Chicago /ID# 200735, Chicago, Illinois, United States
Henry Ford Health System /ID# 202480, Detroit, Michigan, United States
Mayo Clinic - Rochester /ID# 200732, Rochester, Minnesota, United States
Washington University School /ID# 164091, Saint Louis, Missouri, United States
The Ohio State University - Columbus /ID# 164089, Columbus, Ohio, United States
Univ Oklahoma HSC /ID# 164090, Oklahoma City, Oklahoma, United States
Tennessee Oncology-Nashville Centennial /ID# 164088, Nashville, Tennessee, United States
MD Anderson Cancer Center /ID# 200048, Houston, Texas, United States
Huntsman Cancer Institute /ID# 209164, Salt Lake City, Utah, United States
Contact Details
Name: AbbVie Inc.
Affiliation: AbbVie
Role: STUDY_DIRECTOR
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