Spots Global Cancer Trial Database for Efficacy of Caffeine Injection as an Adjuvant to Opioid Therapy in Cancer Pain
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Trial Identification
Brief Title: Efficacy of Caffeine Injection as an Adjuvant to Opioid Therapy in Cancer Pain
Official Title: Efficacy of Caffeine as an Adjuvant to Opioid Therapy in Cancer Pain: a Randomized, Double-blind, Placebo-controlled Trial
Study ID: NCT00879775
Study Description
Brief Summary: Pain is a most common symptom and it has a high impact on quality of life in cancer patients. Many cancer patients have received opioid therapy, but also many of them have suffered from side effects of opioids. Drowsiness and confusion are common side effects of opioids. Caffeine is a well known psychostimulant,and it is widely used as an analgesics. Thus, the investigators aimed to prove the efficacy of intravenous caffeine administration as an adjuvant analgesics to opioids. At the same time, the investigators tried to find that the side effects of opioids could be ameliorated by caffeine.
Detailed Description: Previous studies on cancer pain lacked assessment of quality of life. And most of previous studies on cancer pain did not give attention to symptoms accompanied with pain. We include such variables as outcome measures, and aimed to evaluate the efficacy and the safety of intravenous caffeine in advanced cancer inpatients.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
National Health Insurance Corporation Ilsan Hospital, Goyang-si, Gyeonggi-do, Korea, Republic of
Korea University Guro Hospital, Seoul, , Korea, Republic of
Contact Details
Name: Sang-Yeon Suh, M.D.,Ph.D
Affiliation: DongGuk University
Role: PRINCIPAL_INVESTIGATOR
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