Spots Global Cancer Trial Database for Accelerated Neuromodulation to Alleviate Cognitive Deficits Due to Cancer Therapy

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Trial Identification

Brief Title: Accelerated Neuromodulation to Alleviate Cognitive Deficits Due to Cancer Therapy

Official Title: Repetitive Intermittent Accelerated Theta-burst Transcranial Stimulation(iTBS) as a Potential Intervention for Chemotherapy Induced Cognitive Deficits (CICD)- a Pilot Clinical Trial to Explore Feasibility and Efficacy

Study ID: NCT04966520

Conditions

Cancer

Interventions

Accelerated repetitive intermittent theta-burst transcranial stimulation (iTBS)

Study Description

Brief Summary: This project is aimed at the discovery of neuro-modulation techniques that may alleviate chemotherapy induced cognitive deficits (CICD), especially in executive (higher-order) cognitive function (EF).

Detailed Description: The specific aim for this study is to use magnetic resonance spectroscopy (MRS), self-report, and neuropsychological testing to identify changes in brain metabolite concentrations/ratios and changes in EF deficits associated with chemotherapy, before and after accelerated theta-burst transcranial stimulation (iTBS). The secondary aim is to assess for any association of changes in executive function with brain metabolite concentrations.