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Brief Title: ARQ 197 in Subjects With Metastatic Solid Tumors
Official Title: A Phase 1 Dose Escalation Study of ARQ 197 in Adult Patients With Metastatic Solid Tumors
Study ID: NCT00302172
Brief Summary: To determine the safety, tolerability and recommended Phase 2 dose (RP2D) of ARQ 197.
Detailed Description: To determine the safety, tolerability and recommended Phase 2 dose (RP2D) of ARQ 197 given orally. This is an open label, dose escalation study of ARQ 197 administered orally at a starting dose of 10 mg bid (20 mg/day).
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Premiere Oncology, Santa Monica, California, United States
The Cleveland Clinic, Cleveland, Ohio, United States
Mary Crowley Medical Research Center, Dallas, Texas, United States