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Brief Title: Assessment of Paclitaxel-Induced Neuropathy
Official Title: Validation of a Polygenic Neurotoxicity Risk Score in Patients With Unusually Severe Paclitaxel-Induced Neuropathy
Study ID: NCT01953159
Brief Summary: The purpose of this study is to collect clinical data, blood samples, and self reported symptoms from patients that experience unusually severe neuropathy after treatment with paclitaxel. This data will be used to develop predictive markers for neuropathy. Blood samples will be used to create induced pluripotent stem (iPS) cells and eventually artificial nerve cells to be used to study neuropathy in the lab.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: Yes
University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States
Name: Gini Fleming, MD
Affiliation: University of Chicago
Role: PRINCIPAL_INVESTIGATOR