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Brief Title: Met Non Small Cell Cancer Registry (MOMENT)
Official Title: Disease Registry on Patients With Advanced NSCLC Harboring METex14 Skipping Alterations (MOMENT)
Study ID: NCT05376891
Brief Summary: The purpose of this multi-national disease registry is to collect prospectively (with longitudinal follow-up) high-quality, standardized, and contemporaneous data to capture changes in the non-small cell lung cancer (NSCLC) treatment landscape and outcomes over time. The registry will capture data on participants; demographic, clinical characteristics (including biomarker data), treatment patterns, and effectiveness and safety outcomes for advanced NSCLC with mesenchymal-epithelial transition exon 14 (METex14) participants treated with systemic therapy.
Detailed Description: This is a disease registry, which is an organized system using non-interventional methods to collect data on a patient population defined by a particular disease, exposure, or condition, and which is followed over time. Non-interventional means that after participants enrollment, participants will be treated according to the routine clinical treatment decision by the physician. The registry will not impose any treatment or procedure for participants.
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Holy Cross Health, Fort Lauderdale, Florida, United States
The Ohio State University Wexner Medical Center, Columbus, Ohio, United States
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Klinikum Klagenfurt Am Woerthersee, Klagenfurt am Wörthersee, , Austria
Klinik Floridsdorf, Wien, , Austria
AZ Delta, Roeselare, , Belgium
AZ Nikolaas, Sint-Niklaas, , Belgium
Ottawa Hospital General Campus, Ottawa, , Canada
Princess Margaret Cancer Centre, Toronto, , Canada
FN Olomouc, Olomouc, , Czechia
University Hospital Na Bulovce, Praha 8, , Czechia
University Hospital of Tampere, Tampere, , Finland
Turun Yliopistollinen Keskussairaala, Turku, , Finland
Centre Hospitalier de Cholet, Cholet, , France
CHRU Lille, Lille cedex, , France
Hôpital du Scorff, Lorient, , France
Centre Leon Berard, Lyon Cedex 08, , France
Institut Curie - Centre de Lutte Contre le Cancer (CLCC), Paris Cedex 05, , France
Hospital Tenon & University Paris 6, Paris, , France
CHU de Toulouse Hopital Larrey, Toulouse, , France
Klinikum Chemnitz GmbH, Chemnitz, , Germany
KKH Grosshansdorf GmbH, Grosshansdorf, , Germany
Thoraxklinik-Heidelberg gGmbH, Heidelberg, , Germany
Klinik Löwenstein GmbH, Löwenstein, , Germany
Haemek Medical Center, Afula, , Israel
Assuta Ashdod Medical Center, Ashdod, , Israel
Bnei-Zion Medical Center, Haifa, , Israel
Carmel Medical Center, Haifa, , Israel
Rambam Medical Center - PPDS, Haifa, , Israel
Shaare Zedek Medical Center, Jerusalem, , Israel
Rabin Medical Center Oncology Beilinson Campus, Petach Tikva, , Israel
Chaim Sheba Medical Center, Ramat Gan, , Israel
Tel Aviv Sourasky Medical Center, Tel Aviv, , Israel
Istituto Europeo di Oncologia, Milano, , Italy
Istituto Nazionale Dei Tumori, Milano, , Italy
AOU dell'Università degli Studi della Campania Luigi Vanvitelli, Napoli, , Italy
I.F.O. Istituto Nazionale Tumori Regina Elena IRCCS, Rome, , Italy
Azienda Sanitaria Ospedaliera S Luigi Gonzaga, Torino, , Italy
Ospedale di Circolo, Varese, , Italy
VU Medisch Centrum, Amsterdam, , Netherlands
Universitair Medisch Centrum Groningen - Department of Medical Oncology, Groningen, , Netherlands
Leiden University Medical Center, Leiden, , Netherlands
Centro Hospitalar de Lisboa Norte, EPE - Hospital de Santa Maria, Lisboa, , Portugal
Instituto Portugues de Oncologia Do Porto Francisco Gentil Epe - PPDS, Porto Covo, , Portugal
Centro Hospitalar do Porto E.P.E. Hospital de Santo António, Porto, , Portugal
Clinica Tres Torres, Barcelona, , Spain
Institut Universitari Dexeus-Quiron - Servei d oncologia medica - Institut Oncologic Dr. Rosell, Barcelona, , Spain
Complejo Hospitalario Universitario Insular-Materno Infantil, las Palmas de Gran Canaria, , Spain
Centro Integral Oncologico Clara Campa, Madrid, , Spain
Centro Oncologico MD Anderson, Madrid, , Spain
Hospital Regional Universitario de Malaga - Hospital General, Malaga, , Spain
Hospidal Universitario Ntra. Sra. De Valme, Sevilla, , Spain
Hospital Universitario Virgen Macarena, Sevilla, , Spain
Hospital Universitari i Politecnic La Fe de Valencia, Valencia, , Spain
Universitetssjukhuset i Linköping, Linköping, , Sweden
Bedford General Hospital, Bedford, , United Kingdom
Birmingham Heartlands Hospital, Birmingham, , United Kingdom
Royal Bournemouth Hospital, Bournemouth, , United Kingdom
The Royal Marsden Hospital, Chelsea, , United Kingdom
Royal Surrey County Hospital, Guildford, , United Kingdom
Northwick Park Hospital, Harrow, , United Kingdom
Clatterbridge Cancer Centre - Liverpool, Liverpool, , United Kingdom
Charing Cross Hospital, London, , United Kingdom
Preston Hospital, Preston, , United Kingdom
Name: Medical Responsible
Affiliation: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Role: STUDY_DIRECTOR