Spots Global Cancer Trial Database for Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain
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Trial Identification
Brief Title: Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain
Official Title: Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain: A Randomized, Double-Blind Study
Study ID: NCT00525967
Interventions
Study Description
Brief Summary: The purpose of this study is to determine whether oral methadone plus acetaminophen can substitute morphine in the treatment of cancer pain.
Detailed Description: Opioids are the mainstay of moderate-to-severe cancer pain management. Although morphine is the most commonly used, methadone has some advantages such as higher potency, lower cost and longer administration intervals. To minimize the time necessary to achieve the equianalgesic effect after a switching from morphine to methadone, acetaminophen was added in the treatment.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Disciplina de Oncologia, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil
Contact Details
Name: Daniel IG Cubero
Affiliation: Faculdade de Medicina do ABC
Role: PRINCIPAL_INVESTIGATOR
Name: Auro del Giglio
Affiliation: Faculdade de Medicina do ABC
Role: STUDY_DIRECTOR
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