Spots Global Cancer Trial Database for Study Investigating MEN1 and SDHD in Familial Carcinoid Tumors
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Trial Identification
Brief Title: Study Investigating MEN1 and SDHD in Familial Carcinoid Tumors
Official Title: A Pilot Study to Investigate Germ-Line MEN1 and SDHD Gene Mutation in Familial Cases of Carcinoid Cancer
Study ID: NCT00672269
Conditions
Interventions
Study Description
Brief Summary: There is a high incidence among the first degree relatives of the carcinoid patients, indicating the involvement of genetic components in its initiation and pathogenesis.
Detailed Description: This proposed pilot study will conduct detailed interviews into the medical, environmental, and family histories and to collect blood specimen to obtain DNA. The Blood specimen and DNA will be processed by the Rutgers University Cell and DNA Repository (RUCDR) to rule out Familial Multiple Endocrine Neoplasia (MEN 1), and succinate dehydrogenase complex, subunit D (SDHD), gene inactivation thought to be associated with different types of carcinoid cancer.
Eligibility
Minimum Age: 12 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Busch Campus of Rutgers University, Human Genetics Institute, Piscataway, New Jersey, United States
Contact Details
Name: Nancy Gardner, PhD
Affiliation: Rutgers University
Role: PRINCIPAL_INVESTIGATOR
Name: Changshun Shao, PhD
Affiliation: Rutgers University
Role: PRINCIPAL_INVESTIGATOR
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