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Brief Title: Everolimus and Octreotide in Patients With Advanced Carcinoid Tumor
Official Title: A Randomized, Double-blind Placebo-controlled, Multicenter Phase III Study in Patients With Advanced Carcinoid Tumor Receiving Octreotide Depot and Everolimus 10 mg/Day or Octreotide Depot and Placebo
Study ID: NCT00412061
Brief Summary: The purpose of this study was to evaluate whether everolimus 10 mg / day added to treatment with depot octreotide prolongs progression free survival compared to treatment with octreotide alone in patients with advanced carcinoid tumor.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Arizona / Arizona Cancer Center Deptof Uof A/Arizona Cancer(2), Tucson, Arizona, United States
Highlands Oncology Group The Center for Chest Care, Fayetteville, Arkansas, United States
Hematology Oncology Services of Arkansas, Little Rock, Arkansas, United States
Pacific Cancer Medical Center, Inc., Anaheim, California, United States
Cedars Sinai Medical Center SC-2, Los Angeles, California, United States
University of California at Los Angeles UCLA New SC Address, Los Angeles, California, United States
University of Colorado Dept. of Univ. of Colorado, Aurora, Colorado, United States
Rocky Mountain Cancer Centers Dept of Rocky Mountain (2), Denver, Colorado, United States
Eastern Connecticut Hematology & Oncology Associates Dept. of ECHO, Norwich, Connecticut, United States
Cancer Centers of Connecticut Southington Location, Southington, Connecticut, United States
Hematology Oncology PC Dept.of Hematology Oncology(2), Stamford, Connecticut, United States
Ocala Oncology Center Dept. of Ocala Oncology Center, Ocala, Florida, United States
Cancer Care and Hematology Specialists of Chicagoland Niles, Niles, Illinois, United States
Indiana University Dept.of IndianaUniv.CancerCtr, Indianapolis, Indiana, United States
Central Indiana Cancer Centers CICC - South, Indianapolis, Indiana, United States
University of Iowa Medical Center Internal Medicine, Iowa City, Iowa, United States
University of Kansas Cancer Center Deptof Uof Kansas CancerCenter, Kansas City, Kansas, United States
Kansas City Cancer Center KCCC Business Office, Overland Park, Kansas, United States
Norton Cancer Institute Clinical Research Program, Louisville, Kentucky, United States
LSU HEALTH SCIENCES CENTER/ LSU SCHOOL OF MEDICINE Deptof LSU Health Sciences (2), New Orleans, Louisiana, United States
Mayo Clinic - Rochester Division of Hematology, Rochester, Minnesota, United States
Washington University School Of Medicine-Siteman Cancer Ctr Division of Oncology, St. Louis, Missouri, United States
The Center for Cancer Care and Research, St. Louis, Missouri, United States
Dartmouth Hitchcock Medical Center Medical Oncology, Lebanon, New Hampshire, United States
New York Oncology Hematology, P.C. Dept. of New York Oncology. PC, Albany, New York, United States
New York University Medical Center NYU Medical Center (2), New York, New York, United States
Duke University Medical Center Dept. of Duke Cancer Center, Durham, North Carolina, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Cancer Centers of the Carolinas CC of C -Eastside, Greenville, South Carolina, United States
Texas Oncology, P.A. Central Austin Cancer Center, Austin, Texas, United States
South Texas Institute of Cancer S. Tex Inst.- Corpus Christi, Corpus Christi, Texas, United States
Sammons Cancer Center - Texas Oncology Sammons Cancer Center (SC), Dallas, Texas, United States
Texas Oncology, P.A. Forth Worth -- 12th Avenue, Fort Worth, Texas, United States
University of Texas/MD Anderson Cancer Center Gastrointestinal Med. Oncology, Houston, Texas, United States
Tyler Cancer Center, Tyler, Texas, United States
Virginia Oncology Associates VOA - Lake Wright, Norfolk, Virginia, United States
Northwest Cancer Specialists Compass Oncology -BKM, Vancouver, Washington, United States
University of Wisconsin / Paul P. Carbone Comp Cancer Center GI Oncology Research Center, Madison, Wisconsin, United States
Novartis Investigative Site, Kogarah, New South Wales, Australia
Novartis Investigative Site, Herston, Queensland, Australia
Novartis Investigative Site, South Brisbane, Queensland, Australia
Novartis Investigative Site, Bruxelles, , Belgium
Novartis Investigative Site, London, Ontario, Canada
Novartis Investigative Site, Toronto, Ontario, Canada
Novartis Investigative Site, Montreal, Quebec, Canada
Novartis Investigative Site, Montreal, Quebec, Canada
Novartis Investigative Site, Praha 2, , Czech Republic
Novartis Investigative Site, Pribram, , Czech Republic
Novartis Investigative Site, Helsinki, , Finland
Novartis Investigative Site, Clichy Cédex, , France
Novartis Investigative Site, Lille Cedex, , France
Novartis Investigative Site, Montpellier, , France
Novartis Investigative Site, Paris Cedex 15, , France
Novartis Investigative Site, Strasbourg, , France
Novartis Investigative Site, Toulouse Cedex 9, , France
Novartis Investigative Site, Villejuif Cedex, , France
Novartis Investigative Site, Berlin, , Germany
Novartis Investigative Site, Hamburg, , Germany
Novartis Investigative Site, Athens, , Greece
Novartis Investigative Site, Bologna, BO, Italy
Novartis Investigative Site, Milano, MI, Italy
Novartis Investigative Site, Milano, MI, Italy
Novartis Investigative Site, Perugia, PG, Italy
Novartis Investigative Site, Pisa, PI, Italy
Novartis Investigative Site, Groningen, , Netherlands
Novartis Investigative Site, Rotterdam, , Netherlands
Novartis Investigative Site, Bratislava, Slovak Republic, Slovakia
Novartis Investigative Site, Madrid, , Spain
Novartis Investigative Site, Uppsala, , Sweden
Novartis Investigative Site, Basingstoke, , United Kingdom
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR