Spots Global Cancer Trial Database for A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista
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Trial Identification
Brief Title: A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista
Official Title: A Phase IIIB, Single Arm, Multicenter Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista
Study ID: NCT04487067
Conditions
Study Description
Brief Summary: This is a Phase IIIb, one arm, multicenter, open-label study designed to evaluate the safety and efficacy of atezolizumab + bevacizumab in patients with unresectable HCC who have received no prior systemic treatment.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Fondazione Pascale; U.O. Sperimentazioni Cliniche, Napoli, Campania, Italy
Azienda Osp Uni Seconda Università Degli Studi Di Napoli; Unità Operativa Oncologia Medica, Napoli, Campania, Italy
Ospedale del Mare; UOC di Oncologia, Napoli, Campania, Italy
A.O. S. Orsola Malpighi; Ambulatorio Epatocarcinoma (Bolondi), Bologna, Emilia-Romagna, Italy
Arcispedale Santa Maria Nuova; Oncologia, Reggio Emilia, Emilia-Romagna, Italy
Policlinico Universitario Agostino Gemelli, Roma, Lazio, Italy
Azienda Ospedaliera San Camillo Forlanini, Roma, Lazio, Italy
A.O. Universitaria S. Martino Di Genova, Genova, Liguria, Italy
Ospedali Riuniti - Bergamo; Gastroenterologia, Bergamo, Lombardia, Italy
Fondazione IRCCS Ospedale Maggiore Policlinico; Gastroenterologia, Milano, Lombardia, Italy
Istituto Nazionale Dei Tumori; Dipartimento Chirurgia Generale - Unita' Trapianti Fegato, Milano, Lombardia, Italy
Istituto Clinico Humanitas;U.O. Oncologia Medica Ed Ematologia, Rozzano, Lombardia, Italy
Azienda Ospedaliera Ordine Mauriziano di Torino, Torino, Piemonte, Italy
IRCCS Ospedale Casa Sollievo Della Sofferenza; Oncologia, San Giovanni Rotondo, Puglia, Italy
A.O.U. Cagliari-P.O. Monserrato;U.O. Oncologia, Cagliari, Sardegna, Italy
A.O.U. Policlinico Paolo Giaccone; Gastroenterologia ed Epatologia, Palermo, Sicilia, Italy
Azienda Ospedaliera Di Rilievo Nazionale E Di Alta Specializzazione Garibaldi, Palermo, Sicilia, Italy
A.O.U Careggi, Florence, Toscana, Italy
Azlenda Ospendaliero-Universitaria Pisana; C.O. Oncologia 2, Pisa, Toscana, Italy
Clinica Oncologica-Ospedali Riuniti Ancona, Torrette, Toscana, Italy
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II, Padova, Veneto, Italy
Contact Details
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR
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