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Brief Title: Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM)
Official Title: A Phase III Randomized, Double-blind, Placebo-controlled Study of Sorafenib as Adjuvant Treatment for Hepatocellular Carcinoma After Surgical Resection or Local Ablation.
Study ID: NCT00692770
Brief Summary: To evaluate efficacy and safety of sorafenib versus placebo in the adjuvant treatment of Hepatocellular Carcinoma (HCC) after potentially curative treatment (surgical resection or local ablation).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Birmingham, Alabama, United States
, Phoenix, Arizona, United States
, Los Angeles, California, United States
, Los Angeles, California, United States
, San Francisco, California, United States
, Washington, District of Columbia, United States
, Miami, Florida, United States
, Atlanta, Georgia, United States
, Indianapolis, Indiana, United States
, Louisville, Kentucky, United States
, New Orleans, Louisiana, United States
, Baltimore, Maryland, United States
, Boston, Massachusetts, United States
, Boston, Massachusetts, United States
, Burlington, Massachusetts, United States
, Ann Arbor, Michigan, United States
, Minneapolis, Minnesota, United States
, Minneapolis, Minnesota, United States
, New York, New York, United States
, Cleveland, Ohio, United States
, Cleveland, Ohio, United States
, Columbus, Ohio, United States
Providence Portland Medical Center, Portland, Oregon, United States
, Portland, Oregon, United States
, Pittsburgh, Pennsylvania, United States
, Houston, Texas, United States
, Richmond, Virginia, United States
, Seattle, Washington, United States
, Seattle, Washington, United States
, Pilar, Buenos Aires, Argentina
, Buenos Aires, Ciudad Auton. De Buenos Aires, Argentina
, Rosario, Santa Fe, Argentina
, Camperdown, New South Wales, Australia
, Randwick, New South Wales, Australia
, Brisbane, Queensland, Australia
, Heidelberg, Victoria, Australia
, Melbourne, Victoria, Australia
, Innsbruck, , Austria
, Linz, , Austria
, Wien, , Austria
, Bruxelles - Brussel, , Belgium
, Gent, , Belgium
, Leuven, , Belgium
, Liege, , Belgium
, Porto Alegre, Rio Grande Do Sul, Brazil
, Porto Alegre, Rio Grande Do Sul, Brazil
, Porto Alegre, Rio Grande Do Sul, Brazil
, São Paulo, Sao Paulo, Brazil
, Sao Paulo, , Brazil
, Plovdiv, , Bulgaria
, Varna, , Bulgaria
, Calgary, Alberta, Canada
, Edmonton, Alberta, Canada
, Vancouver, British Columbia, Canada
, Ottawa, Ontario, Canada
, Toronto, Ontario, Canada
, Santiago de Chile, Santiago, Chile
, Reñaca, Valparaíso, Chile
, Guangzhou, Guangdong, China
, Guangzhou, Guangdong, China
, Guangzhou, Guangdong, China
, Nanning, Guangxi, China
, Wuhan, Hubei, China
, Changsha, Hunan, China
, Changsha, Hunan, China
, Nanjing, Jiangsu, China
, Xi'an, Shanxi, China
, Xi'an, Shanxi, China
, Xi'an, Shanxi, China
, Chengdu, Sichuan, China
, Chengdu, Sichuan, China
, Beijing, , China
, Beijing, , China
, Beijing, , China
, Beijing, , China
, Beijng, , China
, Chongqing, , China
, Dalian, , China
, Hefei, , China
, Shanghai, , China
, Shanghai, , China
, Tianjin, , China
, ANGERS cedex 09, , France
, Bondy, , France
, Bordeaux, , France
, Creteil, , France
, Lille, , France
, Lyon, , France
, Marseille, , France
, Nice, , France
, Paris, , France
, Paris, , France
, Rennes, , France
, Toulouse, , France
, Vandoeuvre-les-nancy, , France
, Villejuif, , France
, München, Bayern, Germany
, München, Bayern, Germany
, Regensburg, Bayern, Germany
, Göttingen, Niedersachsen, Germany
, Hannover, Niedersachsen, Germany
, Aachen, Nordrhein-Westfalen, Germany
, Düsseldorf, Nordrhein-Westfalen, Germany
, Essen, Nordrhein-Westfalen, Germany
, Köln, Nordrhein-Westfalen, Germany
, Mainz, Rheinland-Pfalz, Germany
, Homburg/Saar, Saarland, Germany
, Halle/Saale, Sachsen-Anhalt, Germany
, Magdeburg, Sachsen-Anhalt, Germany
, Berlin, , Germany
, Hamburg, , Germany
, Athens / Greece, , Greece
, Hong Kong, , Hong Kong
, Kwun Tong, , Hong Kong
, Shatin, , Hong Kong
, Benevento, Campania, Italy
, Napoli, Campania, Italy
, Napoli, Campania, Italy
, Bologna, Emilia-Romagna, Italy
, Modena, Emilia-Romagna, Italy
, Roma, Lazio, Italy
, Milano, Lombardia, Italy
, Milano, Lombardia, Italy
, Torino, Piemonte, Italy
, Bari, Puglia, Italy
, Cagliari, Sardegna, Italy
, Catania, Sicilia, Italy
, Palermo, Sicilia, Italy
, Padova, Veneto, Italy
, Kashiwa-shi, Chiba, Japan
, Kanazawa, Ishikawa, Japan
, Yokohama-shi, Kanagawa, Japan
, Osakasayama-shi, Osaka, Japan
, Suita, Osaka, Japan
, Bunkyo-ku, Tokyo, Japan
, Chuo-ku, Tokyo, Japan
, Itabashi-ku, Tokyo, Japan
, Minato-ku, Tokyo, Japan
, Shibuya-ku, Tokyo, Japan
, Shinjuku-ku, Tokyo, Japan
, Fukuoka, , Japan
, Kumamoto, , Japan
, Kyoto, , Japan
, Okayama, , Japan
, Osaka, , Japan
, Tokushima, , Japan
, Goyang-si, Gyeonggido, Korea, Republic of
, Goyang-si, Gyeonggido, Korea, Republic of
, Seoul, Seoul Teugbyeolsi, Korea, Republic of
, Busan, , Korea, Republic of
, Daegu, , Korea, Republic of
, Jeollabuk-do, , Korea, Republic of
, Seoul, , Korea, Republic of
, Seoul, , Korea, Republic of
, Seoul, , Korea, Republic of
, Seoul, , Korea, Republic of
, México, D.F., Distrito Federal, Mexico
, Monterrey, Nuevo Leon, Mexico
, México, D.F., , Mexico
, Auckland, , New Zealand
, Coimbra, , Portugal
, Bucharest, , Romania
, Cluj-Napoca, , Romania
, Iasi, , Romania
, Moscow, , Russian Federation
, Moscow, , Russian Federation
, Obninsk, , Russian Federation
, St. Petersburg, , Russian Federation
, Singapore, , Singapore
, Singapore, , Singapore
, Oviedo, Asturias, Spain
, Sabadell, Barcelona, Spain
, Cruces/Barakaldo, Bilbao, Spain
, Barcelona, Catalunya, Spain
, Majadahonda, Madrid, Spain
, Badajoz, , Spain
, Barcelona, , Spain
, Córdoba, , Spain
, Madrid, , Spain
, Madrid, , Spain
, Valladolid, , Spain
, Göteborg, , Sweden
, Stockholm, , Sweden
, Bern, , Switzerland
, Zürich, , Switzerland
, Changhua, , Taiwan
, Kaohsiung City, , Taiwan
, Kaohsung, , Taiwan
, Tainan, , Taiwan
, Taipei, , Taiwan
, Taipei, , Taiwan
, Taoyuan, , Taiwan
, Southampton, Hampshire, United Kingdom
, Birmingham, West Midlands, United Kingdom
, Leeds, West Yorkshire, United Kingdom
, London, , United Kingdom
, London, , United Kingdom
, Manchester, , United Kingdom
, Newcastle Upon Tyne, , United Kingdom
Name: Bayer Study Director
Affiliation: Bayer
Role: STUDY_DIRECTOR