Spots Global Cancer Trial Database for Prospective Surveillance for Very Early Hepatocellular Carcinoma
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Trial Identification
Brief Title: Prospective Surveillance for Very Early Hepatocellular Carcinoma
Official Title: Prospective Surveillance for Very Early Hepatocellular Carcinoma (PRECAR): an Observational Cohort Trial
Study ID: NCT03588442
Conditions
Interventions
Study Description
Brief Summary: Hepatocellular carcinoma is one the leading cause of increasing cancer-specific mortality worldwide. Early diagnosis of hepatocellular carcinoma provides opportunity for curative therapeutic approaches and relatively favorable prognosis. Herein, we intended to establish a biosignature for early diagnosis of hepatocellular carcinoma and stratification of risk population for intensive follow-up by implementing biannual follow-up investigation and collecting peripheral blood samples for screening.
Detailed Description: Patients will be recruited for 1 year and be follow-up for 3 years. Patients will make active hospital visit for collection of blood samples, which will be analyzed to develop a biosignature at the end of the study to detect very early hepatocellular carcinoma and stratify risk population for intensive follow-up.
Keywords
Eligibility
Minimum Age: 30 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
The First Hospital Affiliated to AMU (Southwest Hospital), Chongqing, Chongqing, China
Mengchao Hepatobiliary Surgery Hospital of Fujian Medical University, Fuzhou, Fujian, China
Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
The Central Hospital of Wuhan, Wuhan, Hubei, China
Chifeng Municipal Hospital, Chifeng, Inner Mongolia, China
Xuzhou No.1 People's Hospital, Xuzhou, Jiangsu, China
Xuzhou Infectious Disease Hospital, Xuzhou, Jiangsu, China
The First Bethune of Jilin University, Changchun, Jilin, China
The Second Hospital of Shandong University, Jinan, Shandong, China
Shanghai Public Health Clinical Center, Shanghai, Shanghai, China
Shanghai Oriental Hepatobiliary Surgery Hospital, Shanghai, Shanghai, China
First Affiliated Hospital, Xinjiang Medical University, Ürümqi, Xinjiang, China
HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China
Contact Details
Name: Hongyang Wang, MD and PhD
Affiliation: Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China
Role: PRINCIPAL_INVESTIGATOR
Name: Jinlin Hou, MD
Affiliation: Nanfang Hospital, Southern Medical University
Role: PRINCIPAL_INVESTIGATOR
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