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Brief Title: Phase I/II Comparison of Efficacy and Safety of BIBF 1120 and Sorafenib in Patients With Advanced Hepatocellular Carcinoma
Official Title: A Multicenter, Open Label, Phase I /Randomised Phase II Study to Evaluate Safety, Pharmacokinetics and Efficacy of BIBF 1120 in Comparison With Oral Sorafenib for Advanced Hepatocellular Carcinoma Patients.
Study ID: NCT01004003
Brief Summary: The study aim is to determine maximally tolerated dose (MTD) of BIBF 1120 in HCC (hepatocellular cancer) and compare efficacy of BIBF 1120 to Sorafenib in HCC patients
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
1199.37.43001 Boehringer Ingelheim Investigational Site, Wien, , Austria
1199.37.43002 Boehringer Ingelheim Investigational Site, Wien, , Austria
1199.37.33001 Boehringer Ingelheim Investigational Site, Paris, , France
1199.37.33002 Boehringer Ingelheim Investigational Site, Paris, , France
1199.37.49008 Boehringer Ingelheim Investigational Site, Berlin, , Germany
1199.37.49009 Boehringer Ingelheim Investigational Site, Erlangen, , Germany
1199.37.49002 Boehringer Ingelheim Investigational Site, Freiburg, , Germany
1199.37.49001 Boehringer Ingelheim Investigational Site, Hannover, , Germany
1199.37.49010 Boehringer Ingelheim Investigational Site, Heidelberg, , Germany
1199.37.49005 Boehringer Ingelheim Investigational Site, Jena, , Germany
1199.37.49004 Boehringer Ingelheim Investigational Site, Magdeburg, , Germany
1199.37.49003 Boehringer Ingelheim Investigational Site, München, , Germany
1199.37.49006 Boehringer Ingelheim Investigational Site, Tübingen, , Germany
1199.37.36001 Boehringer Ingelheim Investigational Site, Debrecen, , Hungary
1199.37.31002 Boehringer Ingelheim Investigational Site, Leiden, , Netherlands
1199.37.31001 Boehringer Ingelheim Investigational Site, Utrecht, , Netherlands
1199.37.48002 Boehringer Ingelheim Investigational Site, Olsztyn, , Poland
1199.37.48003 Boehringer Ingelheim Investigational Site, Warsaw, , Poland
1199.37.48001 Boehringer Ingelheim Investigational Site, Warszawa, , Poland
1199.37.40002 Boehringer Ingelheim Investigational Site, Bucharest, , Romania
1199.37.40003 Boehringer Ingelheim Investigational Site, Cluj-Napoca, , Romania
1199.37.44001 Boehringer Ingelheim Investigational Site, Edgbaston, Birmingham, , United Kingdom
1199.37.44005 Boehringer Ingelheim Investigational Site, Glasgow, , United Kingdom
1199.37.44008 Boehringer Ingelheim Investigational Site, Liverpool, , United Kingdom
1199.37.44002 Boehringer Ingelheim Investigational Site, London, , United Kingdom
1199.37.44003 Boehringer Ingelheim Investigational Site, London, , United Kingdom
1199.37.44006 Boehringer Ingelheim Investigational Site, Manchester, , United Kingdom
1199.37.44004 Boehringer Ingelheim Investigational Site, Nottingham, , United Kingdom
Name: Boehringer Ingelheim
Affiliation: Boehringer Ingelheim
Role: STUDY_CHAIR