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Spots Global Cancer Trial Database for Characterizing Disease Biology, Treatment and Toxicity in Older Adults With Hepatocellular Carcinoma

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Characterizing Disease Biology, Treatment and Toxicity in Older Adults With Hepatocellular Carcinoma

Official Title: Characterizing Disease Biology, Treatment Patterns and Toxicity in Older Adults With Advanced Hepatocellular Carcinoma

Study ID: NCT03894917

Study Description

Brief Summary: This is an observational, prospective cohort study that will recruit a diverse sample of 84 participants with newly diagnosed with unresectable, advanced hepatocellular carcinoma (HCC) at the UT Health Cancer Center in San Antonio. This study uses geriatric assessment tools with participants 65 years and older and collects adverse events and exploratory markers of aging for all participants.

Detailed Description: The results from this study will allow us to identify unique disease characteristics of older participants and to study treatment patterns that may be barriers to treatment and risk factors for increased morbidity. Characteristics of Comprehensive Geriatric Assessment will be obtained prior to standard interventional treatment for participants that are 65 years or older. Observations will be made of treatment toxicities and cellular senescence with treatment outcomes. Findings from this study will result in the development of R01 intervention studies that develop and validate a treatment algorithm based on these associations to provide older adults with a personalized treatment plan.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mays Cancer Center, San Antonio, Texas, United States

Contact Details

Name: Sukeshi Patel Arora, MD

Affiliation: Mays Cancer Center

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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