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Spots Global Cancer Trial Database for Trial Of CP-751, 871 And Erlotinib In Refractory Lung Cancer

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Trial Identification

Brief Title: Trial Of CP-751, 871 And Erlotinib In Refractory Lung Cancer

Official Title: Randomized, Open Label, Phase 3 Trial Of Erlotinib Alone Or In Combination With CP-751,871 In Patients With Advanced Non Small Cell Lung Cancer Of Non Adenocarcinoma Histology

Study ID: NCT00673049

Conditions

Carcinoma, Large Cell

Carcinoma, Non-Small-Cell Lung

Carcinoma, Squamous Cell

Carcinoma, Adenosquamous Cell

Interventions

CP 751,871 (Figitumumab)

Erlotinib

Study Description

Brief Summary: The objective of this study is to test a clinical benefit of the addition of CP 751,871 to erlotinib therapy in patients with advanced NSCLC of non adenocarcinoma histology. The primary endpoint is Overall Survival (OS).

Detailed Description: This study was terminated on March 8, 2010 due to an analysis by an independent Data Safety Monitoring Committee (DSMC) indicating that the addition of CP-751,871 \[figitumumab\] to erlotinib \[Tarceva\] would be unlikely to meet the primary endpoint of improving overall survival when compared to erlotinib alone. This Oncology study continues as terminated, however for ethical reasons some patients, noted with resultant benefit, continue receiving treatment.

Keywords

IGR-1R

Non small cell lung cancer

CP-751

871

Figitumumab

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Pfizer Investigational Site, Fort Smith, Arkansas, United States

Pfizer Investigational Site, Hot Springs, Arkansas, United States

Pfizer Investigational Site, Lakeport, California, United States

Pfizer Investigational Site, Orange, California, United States

Pfizer Investigational Site, Petaluma, California, United States

Pfizer Investigational Site, Santa Rosa, California, United States

Pfizer Investigational Site, Thousand Oaks, California, United States

Pfizer Investigational Site, Westlake Valley, California, United States

Pfizer Investigational Site, Denver, Colorado, United States

Pfizer Investigational Site, Lafayette, Colorado, United States

Pfizer Investigational Site, Hollywood, Florida, United States

Pfizer Investigational Site, Lake City, Florida, United States

Pfizer Investigational Site, Pembroke Pines, Florida, United States

Pfizer Investigational Site, Alpharetta, Georgia, United States

Pfizer Investigational Site, Atlanta, Georgia, United States

Pfizer Investigational Site, Conyers, Georgia, United States

Pfizer Investigational Site, Cumming, Georgia, United States

Pfizer Investigational Site, Decatur, Georgia, United States

Pfizer Investigational Site, Duluth, Georgia, United States

Pfizer Investigational Site, Lake Spivey, Georgia, United States

Pfizer Investigational Site, Lawrenceville, Georgia, United States

Pfizer Investigational Site, Snellville, Georgia, United States

Pfizer Investigational Site, Bloomington, Illinois, United States

Pfizer Investigational Site, Peoria, Illinois, United States

Pfizer Investigational Site, Beech Grove, Indiana, United States

Pfizer Investigational Site, Indianapolis, Indiana, United States

Pfizer Investigational Site, Cedar Rapids, Iowa, United States

Pfizer Investigational Site, Waterloo, Iowa, United States

Pfizer Investigational Site, Louisville, Kentucky, United States

Pfizer Investigational Site, Bethesda, Maryland, United States

Pfizer Investigational Site, New Albany, Mississippi, United States

Pfizer Investigational Site, Billings, Montana, United States

Pfizer Investigational Site, Butte, Montana, United States

Pfizer Investigational Site, Lebanon, New Hampshire, United States

Pfizer Investigational Site, Manchester, New Hampshire, United States

Pfizer Investigational Site, Amherst, New York, United States

Pfizer Investigational Site, Bronx, New York, United States

Pfizer Investigational Site, Buffalo, New York, United States

Pfizer Investigational Site, Lake Success, New York, United States

Pfizer Investigational Site, Manhasset, New York, United States

Pfizer Investigational Site, New Hyde Park, New York, United States

Pfizer Investigational Site, Columbus, Ohio, United States

Pfizer Investigational Site, Norman, Oklahoma, United States

Pfizer Investigational Site, Oklahoma City, Oklahoma, United States

Pfizer Investigational Site, Tulsa, Oklahoma, United States

Pfizer Investigational Site, Philadelphia, Pennsylvania, United States

Pfizer Investigational Site, Germantown, Tennessee, United States

Pfizer Investigational Site, San Antonio, Texas, United States

Pfizer Investigational Site, Charlottesville, Virginia, United States

Pfizer Investigational Site, Gloucester, Virginia, United States

Pfizer Investigational Site, Glouster, Virginia, United States

Pfizer Investigational Site, Newport News, Virginia, United States

Pfizer Investigational Site, Williamsburg, Virginia, United States

Pfizer Investigational Site, Wenatchee, Washington, United States

Pfizer Investigational Site, Wheeling, West Virginia, United States

Pfizer Investigational Site, Cody, Wyoming, United States

Pfizer Investigational Site, Brasschaat, , Belgium

Pfizer Investigational Site, Mons, , Belgium

Pfizer Investigational Site, Rio de Janeiro, RJ, Brazil

Pfizer Investigational Site, Porto Alegre, RS, Brazil

Pfizer Investigational Site, Higienopolis, Sao Paulo/ Brazil, Brazil

Pfizer Investigational Site, Santo André, SP, Brazil

Pfizer Investigational Site, Sao Paulo, SP, Brazil

Pfizer Investigational Site, São Paulo, SP, Brazil

Pfizer Investigational Site, Sofia, , Bulgaria

Pfizer Investigational Site, Varna, , Bulgaria

Pfizer Investigational Site, Toronto, Ontario, Canada

Pfizer Investigational Site, Montreal, Quebec, Canada

Pfizer Investigational Site, Independencia, Santiago, RM, Chile

Pfizer Investigational Site, Kutna Hora, , Czech Republic

Pfizer Investigational Site, Nova Ves pod Plesi, , Czech Republic

Pfizer Investigational Site, Praha 8, , Czech Republic

Pfizer Investigational Site, Tabor, , Czech Republic

Pfizer Investigational Site, Rennes, Cedex 9, France

Pfizer Investigational Site, BREST Cedex, , France

Pfizer Investigational Site, La Tronche, , France

Pfizer Investigational Site, Lille, , France

Pfizer Investigational Site, Marseille Cedex 09, , France

Pfizer Investigational Site, Marseille Cedex 20, , France

Pfizer Investigational Site, Saint Pierre la Réunion Cedex, , France

Pfizer Investigational Site, St Priest En Jarez Cedex, , France

Pfizer Investigational Site, Villejuif, , France

Pfizer Investigational Site, Heraklion, Crete, Greece

Pfizer Investigational Site, Larisa, , Greece

Pfizer Investigational Site, Budapest, , Hungary

Pfizer Investigational Site, Matrahaza, , Hungary

Pfizer Investigational Site, Szekesfehervar, , Hungary

Pfizer Investigational Site, Jakarta, DKI Jakarta, Indonesia

Pfizer Investigational Site, Surabaya, East Java, Indonesia

Pfizer Investigational Site, Cork, , Ireland

Pfizer Investigational Site, Dublin 24, , Ireland

Pfizer Investigational Site, Dublin, , Ireland

Pfizer Investigational Site, Avellino, , Italy

Pfizer Investigational Site, Aviano (PN), , Italy

Pfizer Investigational Site, Cattolica (RN), , Italy

Pfizer Investigational Site, Modena, , Italy

Pfizer Investigational Site, Orbassano (TO), , Italy

Pfizer Investigational Site, Padova, , Italy

Pfizer Investigational Site, Rimini, , Italy

Pfizer Investigational Site, Roma, , Italy

Pfizer Investigational Site, Gyeonggi-do, , Korea, Republic of

Pfizer Investigational Site, Seoul, , Korea, Republic of

Pfizer Investigational Site, Riga, , Latvia

Pfizer Investigational Site, Bydgoszcz, , Poland

Pfizer Investigational Site, Gdansk, , Poland

Pfizer Investigational Site, Krakow, , Poland

Pfizer Investigational Site, Lublin, , Poland

Pfizer Investigational Site, Olsztyn, , Poland

Pfizer Investigational Site, Rybnik, , Poland

Pfizer Investigational Site, Wodzislaw Sl., , Poland

Pfizer Investigational Site, Ponce, , Puerto Rico

Pfizer Investigational Site, Cluj-Napoca, Cluj, Romania

Pfizer Investigational Site, Cluj-Napoca, , Romania

Pfizer Investigational Site, Iasi, , Romania

Pfizer Investigational Site, Krasnodar, , Russian Federation

Pfizer Investigational Site, Moscow, , Russian Federation

Pfizer Investigational Site, Sochi, , Russian Federation

Pfizer Investigational Site, St-Petersburg, , Russian Federation

Pfizer Investigational Site, St. Petersburg, , Russian Federation

Pfizer Investigational Site, Belgrade, , Serbia

Pfizer Investigational Site, Sremska Kamenica, , Serbia

Pfizer Investigational Site, Ljubljana, , Slovenia

Pfizer Investigational Site, Bloemfontein, , South Africa

Pfizer Investigational Site, Cape Town, , South Africa

Pfizer Investigational Site, Elche, Alicante, Spain

Pfizer Investigational Site, Oviedo, Asturias, Spain

Pfizer Investigational Site, L'hospitalet de Llobregat, Barcelona, Spain

Pfizer Investigational Site, Manresa, Barcelona, Spain

Pfizer Investigational Site, Sabadell, Barcelona, Spain

Pfizer Investigational Site, Barcelona, , Spain

Pfizer Investigational Site, Girona, , Spain

Pfizer Investigational Site, Madrid, , Spain

Pfizer Investigational Site, Sevilla, , Spain

Pfizer Investigational Site, Basel, , Switzerland

Pfizer Investigational Site, CH-4101 Bruderholz, , Switzerland

Pfizer Investigational Site, Chur, , Switzerland

Pfizer Investigational Site, Liestal, , Switzerland

Pfizer Investigational Site, Taichung, , Taiwan

Pfizer Investigational Site, Taipei, , Taiwan

Pfizer Investigational Site, Taoyuan County, , Taiwan

Pfizer Investigational Site, Dnipropetrovsk, , Ukraine

Pfizer Investigational Site, Donetsk, , Ukraine

Pfizer Investigational Site, Kharkiv, , Ukraine

Pfizer Investigational Site, Kyiv, , Ukraine

Pfizer Investigational Site, Sumy, , Ukraine

Pfizer Investigational Site, Sutton, Surrey, United Kingdom

Pfizer Investigational Site, London, , United Kingdom

Pfizer Investigational Site, Manchester, , United Kingdom

Contact Details

Name: Pfizer CT.gov Call Center

Affiliation: Pfizer

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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